Herpes Zoster Oticus, Ophthalmicus, and Cutaneous Disseminated: Case Report and Literature Review

Abstract

Herpes zoster (HZ) is related with the reactivation of latent varicella-zoster virus (VZV) infection. This infection is associated with HZ-oticus, HZ-ophthalmicus, and disseminated-cutaneous HZ. Here, we report a case of an adolescent male who presented with vesicular-eruptions in the leftforehead. The physical examination showed vesicles on the left V1-dermatome and external auditory canal, associated with ipsilateral periorbital oedema, peripheral VII nerve paralysis, hyperacusis, and tinnitus. Acyclovir, eye lubrication, and ophthalmic prednisolone were started. On second admission day, he developed vesicular lesions throughout the body. Polymerase chain reaction (PCR) of the draining vesicles was VZV-positive.

Retrospective evaluation of clinical features in hospitalized herpes zoster patients

“…DHZ develops as hematogenous dissemination of VZV from the dorsal root ganglia. It is especially seen in patients with cellular immune disorders (9). Although dissemination is more common in immunosuppressive patients, it can also be seen in immunocompetent patients.…”

Neurotrophic corneal ulcer and iridocyclitis directly preceding Ramsay-Hunt Syndrome

“…The authors suggested a similar mechanism as with our patient, that the affected sensory nerves can affect adjacent cranial nerves through anastomoses in the brainstem and even the spinal ganglia. 9 …”

Neuropathic Pain in Neurologic Disorders: A Narrative Review

“…Neuropathic pain can be readily classified as peripheral or central. Peripheral neuropathic pain includes postamputation pain (sometimes called “phantom limb pain”), trigeminal neuralgia, painful radiculopathy, painful polyneuropathy, postherpetic neuralgia (including the optical form [ 58 ]), peripheral neuropathy, and peripheral nerve injury pain. Central neuropathic pain includes post-stroke pain, neuropathic pain associated with spinal cord injury, and central pain syndromes involved in MS [ 57 , 59 , 60 ].…”

“…Despite ongoing efforts to better understand the etiology, diagnosis, and treatment of neuropathic pain, many patients do not receive adequate analgesia for their neuropathic pain. The prevalence of neuropathic pain in the general population has been estimated at 7-8%; however, this number must be considered cautiously, as we lack validated diagnostic criteria for use in surveys of the general population [ 58 ]. Two large surveys of the general population in the United Kingdom and France estimated neuropathic pain prevalence at 8.2% and 6.9%, respectively [ 61 , 62 ].…”