Herpes Zoster May Be a Marker for COVID-19 Infection During Pregnancy

Abstract

The vesicular rash of coronavirus disease 2019 (COVID-19) has been reported to have different forms of presentation. • Pregnant women appear to be at increased risk for complications from COVID-19 infection. • The clinical presentation of herpes zoster should be carefully monitored and reported for further assessment, especially if associated with other signs of COVID-19 infection.

Alternation in the cutaneous microbiome of herpes zoster lesion in a patient with severe coronavirus disease 2019

“…The patient had sufficient antibody titers against the HZ virus, but HZ progressed rapidly and developed into the generalized type. Compared to previous reports of COVID-19 with HZ, [3][4][5]…”

Herpes zoster and COVID-19 infection: a coincidence or a causal relationship?

“…Thirteen patients (45%) were men, and 16 (55%) women (Table 1). A rash involving trigeminal nerve distribution was observed in 12 patients (41.3%), of whom 7 were reported to have HZ ophthalmicus [8][9][10][11][12]. None of the cases had generalized HZ; however, one patient was reported to have multi-metameric involvement of the left scapular and right inguinal area [13].…”

“…Immunosuppression was reported in two patients: a 70-year-old man with cardiac transplant and a 70-year-old woman with myasthenia gravis and diabetes mellitus (on prednisolone and tacrolimus) [ 9 , 14 ]. One patient was pregnant (32 weeks) [ 11 ]. The onset of HZ rash related to COVID-19-associated typical symptoms was variable, ranging from 2 days before COVID-19 symptoms to 70 days after the symptoms, averaging 17 days after COVID-19.…”

“…Systemic antiviral medications were used to treat all patients, except two who were treated with analgesics only [6,[8][9][10][11][12][13][14][15][18][19][20]. Intravenous acyclovir was used to treat 3 patients [8,14,18].…”

Dermatology in a multidisciplinary approach with infectious disease and obstetric medicine against COVID-19

“… Bhargava, Sarkar and Kroumpouzos, 2020c , Daneshgaran, Dubin and Gould, 2020 , Dotters-Katz and Hughes, 2020 , Elsaie, Youssef and Nada, 2020 , Goren et al, 2020b , Kaya, Kaya and Saurat, 2020 , Mehta, Chen and Kroumpouzos, 2016 , Mosby, Rasmussen and Jamieson, 2011 , Bhargava, Gupta and Kroumpouzos, 2020a , Subramanian, Anand and Adderley, 2021 , Tan, Tam and Oh, 2021 , Bhargava, Mckeever and Kroumpouzos, 2021a , Zhu et al, 2020 , Yale et al, 2021 …”