Herpes Zoster Laryngis with Prelaryngeal Skin Erythema

Wu, Chin-Lung; Linne, Oan-Che; Chiang, Ching-Wen

doi:10.1177/000348940411300205

Cited by 22 publications

(15 citation statements)

References 4 publications

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“…Many patients experience hearing loss and vestibulo-cochlear symptoms such as tinnitus and vertigo [418, 420, 425, 426]. The seventh and eighth cranial nerves are most commonly affected [420, 427], but many atypical cranial neuropathies have also been identified [428–431]; Ramsay Hunt syndrome has been associated with dysphonia [46, 424, 429, 432, 433], laryngitis [434, 435], loss of taste [436], chronic cough [437], hiccups [435, 438], dysphagia [46, 424, 429, 439], and persistent vomiting [438]. Other rare complications include jugular foramen syndrome [440] and non-facial neuromotor deficits [441].…”

Section: Complicating Presentations and Disease Associationsmentioning

confidence: 99%

Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific

et al. 2017

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BackgroundHerpes zoster (HZ) is a prevalent viral disease that inflicts substantial morbidity and associated healthcare and socioeconomic burdens. Current treatments are not fully effective, especially among the most vulnerable patients. Although widely recommended, vaccination against HZ is not routine; barriers in Asia-Pacific include long-standing neglect of adult immunisation and sparse local data. To address knowledge gaps, raise awareness, and disseminate best practice, we reviewed recent data and guidelines on HZ from the Asia-Pacific region.MethodsWe searched PubMed, Scopus, and World Health Organization databases for articles about HZ published from 1994 to 2014 by authors from Australia, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, New Zealand, the Philippines, Singapore, Taiwan, Thailand, and Vietnam. We selected articles about epidemiology, burden, complications, comorbidities, management, prevention, and recommendations/guidelines. Internet searches retrieved additional HZ immunisation guidelines.ResultsFrom 4007 retrieved articles, we screened-out 1501 duplicates and excluded 1264 extraneous articles, leaving 1242 unique articles. We found guidelines on adult immunisation from Australia, India, Indonesia, Malaysia, New Zealand, the Philippines, South Korea, and Thailand.HZ epidemiology in Asia-Pacific is similar to elsewhere; incidence rises with age and peaks at around 70 years – lifetime risk is approximately one-third. Average incidence of 3–10/1000 person-years is rising at around 5% per year. The principal risk factors are immunosenescence and immunosuppression. HZ almost always causes pain, and post-herpetic neuralgia is its most common complication. Half or more of hospitalised HZ patients have post-herpetic neuralgia, secondary infections, or inflammatory sequelae that are occasionally fatal. These disease burdens severely diminish patients’ quality of life and incur heavy healthcare utilisation.ConclusionsSeveral countries have abundant data on HZ, but others, especially in South-East Asia, very few. However, Asia-Pacific countries generally lack data on HZ vaccine safety, efficacy and cost-effectiveness. Physicians treating HZ and its complications in Asia-Pacific face familiar challenges but, with a vast aged population, Asia bears a unique and growing burden of disease. Given the strong rationale for prevention, most adult immunisation guidelines include HZ vaccine, yet it remains underused. We urge all stakeholders to give higher priority to adult immunisation in general and HZ in particular.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-017-2198-y) contains supplementary material, which is available to authorized users.

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Section: Complicating Presentations and Disease Associationsmentioning

confidence: 99%

Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific

et al. 2017

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“…6,8 Neurologic attacks that lead to paralysis in the head and neck region is common, especially involving the facial and acoustic nerves. 1 Occasionally, this disease can be accompanied by symptoms of other cranial nerve dysfunction syndromes, such as impaired orbital movement, facial hyperesthesia/pain, dysphagia, vocal paralysis, and tongue paralysis.…”

Section: Discussionmentioning

confidence: 99%

“…It is important to differentiate herpes zoster laryngitis from other diseases to make a correct diagnosis. 1,2,6,8 Herpes zoster laryngitis sometimes presents with unilateral laryngeal edema and vocal fold paralysis, suggesting a laryngeal tumor, laryngeal tuberculosis, fungal infection, syphilis, abscess, or nonspecific laryngeal inflammation, thus making a differential diagnosis necessary. 1,8 Moreover, in the case of unilaterally widespread cranial nerve involvement, malignant infiltration or sarcoidosis should be excluded.…”

Section: Discussionmentioning

confidence: 99%

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Herpes Zoster Laryngitis Accompanied by Ramsay Hunt Syndrome

Lee¹,

Yoon²,

Lee³

et al. 2013

Journal of Craniofacial Surgery

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The most common presentation of herpes zoster in the head and neck region is called Ramsay Hunt syndrome (RHS), which rarely accompanies multiple cranial neuropathy. Herpes zoster also involves the mucous membrane of the tongue, palate, pharynx, and larynx. Herpes zoster infection of the larynx accompanied by Ramsay Hunt syndrome with cranial polyneuropathy is extremely rare, with only few reported cases in the literature. At the time of this report, a review of the medical literature disclosed 4 reported cases of herpes zoster laryngitis accompanied by Ramsay Hunt syndrome. Herein, we present 2 additional cases and report the clinical outcome of cranial polyneuropathy with a review of the literature.

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“…However, to our knowledge, vagus nerve palsy associated with VZV infection without rash has not been reported previously. Because early treatment, including antiviral therapy and corticosteroids, can improve the prognosis [7,12,15] …”

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confidence: 99%

Vagus nerve palsy caused by varicella zoster virus infection without rash

et al. 2007

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Introduction: Varicella Zoster Virus (VZV) is associated with many disorders of the central and peripheral nervous systems including neuralgia, meningitis, meningoencephalitis, cerebel-litis, vasculopathy, myelopathy, Ramsay-Hunt syndrome, and polyneuritis cranialis. Cranial nerves V, VI, VII, VIII, IX, X, XI, and/or XII may be affected. The neurological disorders caused by VZV usually present with rash, but may rarely present without rash. Case report: We herein present a case of polyneuritis cranialis without rash caused by VZV affecting cranial nerves VII, VIII, IX, and X. After excluding other causes of the condition, we diagnosed VZV infection based on VZV DNA in the CSF and an elevated anti-VZV IgG level in serum. The patient responded well to antiviral therapy. Conclusion: VZV infection should be kept in mind during the differential diagnosis of polyneuritis cranialis; it is important to note that VZV re-activation may occur without rash.

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Herpes Zoster Laryngis with Prelaryngeal Skin Erythema

Cited by 22 publications

References 4 publications

Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific

Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific

Herpes Zoster Laryngitis Accompanied by Ramsay Hunt Syndrome

Vagus nerve palsy caused by varicella zoster virus infection without rash

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