Herpes Simplex Virus Conjunctival Ulceration

Conjunctival geographic ulcer: An overlooked sign of herpes simplex virus infection

“…Based on viral isolation, PCR and serologic tests, a definitive primary HSV-1 infection was diagnosed in Patient 1 in this study. Except one case in the pre-acyclovir era [7,8], most cases in the literature responded well to treatment with minimal residual sequelae, indicating that with early recognition of the sign and proper management, a good visual outcome can usually be anticipated [9][10][11][12][13][14][15].…”

“…To date, dendritic or geographic conjunctival ulcers have rarely been reported, and illustrative figures are limited (Table 1) [7][8][9][10][11][12][13][14][15][16]. Therefore this sign is unfamiliar to young ophthalmologists.…”

“…Steroid treatment also has preceded the clinical manifestation in some of the literature [7][8][9][10]15,16]. With injudicious steroid use, the prognosis could be devastating.…”