Herpes simplex keratitis in children.

Abstract

Ophthalmic findings are reported in 31 eyes of 28 children with herpes simplex keratitis. Twenty two had dendritic ulcers, and nine had geographic ulcers or disciform stromal keratitis. After resolution of keratitis, 80% (19/22) of children with dendritic ulcers achieved corrected visual acuity of6/9 or better, 50% (11/22) had induced astigmatism, 45% (9/22) had one to five recurrences. In the group with geographic or disciform lesions, 89% (8/9) had reduced corrected vision, 78% (7/9) had induced astigmatism which was predominantly against the rule, and 87% (7/9) had one to six recurrences.

Pediatric Herpes Simplex Virus Keratitis

“…The rate of bilateral involvement in the larger series of children was 10%226% 3,4,6,8 (Table 2), which is higher than one would expect in a similar cohort of adults 2,13,14 and higher than that in our series. In our series of 29 children, only 1 patient (3%) had bilateral keratitis.…”

“…Thus, in about 80% of our patients the keratitis was recurrent in nature. The recurrence rate in children was also higher in previous reports [3][4][5][6][7][8] (Table 2) than one would expect in a similar cohort of adults. 1,[15][16][17][18][19] On the basis of the Kaplan-Meier estimator, median recurrence time (ie, the time needed for an ocular recurrence to develop in 50% of patients) was 47 months of follow-up in our study; in contrast to the 12 months of followup found by Chong et al 8 Two possible reasons may explain why the recurrence interval in our study is longer.…”

“…3 Only a few studies of HSV keratitis in children have been reported. [3][4][5][6][7][8] This study focused on the clinical features, recurrence, treatment modalities, and visual outcome of children with HSV keratitis in a tertiary referral center in Taiwan.…”

Treatment of Ocular Inflammation in Children

“…Brief taken into consideration for individuals who have been diagnosed use of a weak topical corticosteroid, such as loteprednol etabonate with atypical herpes simplex keratitis unresponsive to antiviral ophthalmic solution (Alrex ® ) can be used in more severe cases, therapy, as dendritiform lesions can present in both forms of and oral antihistamines, nasal corticosteroids, and nasal cromolyn keratitis. [3] Beigi and colleagues [4] found that children who develsodium are indicated for the other symptoms of allergy.…”

Herpetic Keratouveitis in Children

“…3 Although most often unilateral, herpetic keratitis in children can affect both eyes and bilateral involvement has been described in 10% to 26% of children. 2,3,[17][18][19][20] Neonatal herpetic ocular infection, in contrast is frequently bilateral and tends to occur between 2 days to 2 weeks of age. 21 In 30% of cases, mothers of infected neonates show signs or symptoms of HSV genital infection at the time of delivery.…”