Herpes associated erythema multiforme

Abstract

Erythema multiforme is an acute and a self-limiting mucocutaneous hypersensitivity reaction triggered by certain infections and medications. One of the most common predisposing factors for erythema multiforme is infection with herpes simplex virus. Herpes associated erythema multiforme (HAEM) is an acute exudative dermatic and mucosal disease caused by the infecting herpes simplex virus. It has recurrence and idiorestriction, characterized by increasing of CD4+T leukomonocyte. This article reports a case of HAEM in a 9-year-old girl, with a review of relevant literature, and discusses the pathophysiology and treatment of erythema multiforme triggered by herpes simplex virus

Minor Erythema Multiforme Case Report

“…Oral antihistamines and topical steroids provide symptomatic relief. Severe cases require intensive management with systemic steroids and intravenous fluid replacement [11], Recurrence is seen approximately in 20-25% of case with two to four episodes a year [12]. In this case the clinical presentation goes with erythema multiforme minor, regarding the symptoms there was also burning sensation and difficulty in eating swallowing due to the oral and perioral ulcerations.…”

Herpes Associated Erythema Multiforme: A Case Report

“…9 Serology to identify HSV 1 and HSV 2 and to detect specific IgM and IgG antibodies may confirm a suspected history of HSV infection. 8 The diagnosis of HAEM is, however, clinical and is easier when the patient develops target lesions with a preceding or coexisting HSV infection. The finding of typical skin or oral lesions, or both as in our case, supports the clinical diagnosis of HAEM.…”

“…The binding of HSV-containing mononuclear cells to endothelial cells and contribute to the dermal inflammatory response. 8 Both HSV 1 and HSV 2 trigger the erythema multiforme lesion. A study revealed that cutaneous lesions of patients of HAEM were infected with HSV 1 in 66.7% cases, by HSV 2 in 27.8% and both HSV 1 and HSV 2 in 5.6% cases.…”

Treatment of a Pregnant Patient with Herpes Associated Erythema Multiforme (HAEM): A case report

“…herpes associated erythema multiforme -HAEM). Najčešći uzročnik upravo je infekcija HSV-om (HSV-1 i 2) (1,3,4).…”

“…EM is characterized by skin target lesions, and occasionally EM may only involve the oral cavity. One predisposing factor for EM is an infection with herpes simplex virus (HSV), called herpes associated erythema multiforme (HAEM) and the most common trigger for the development of EM is HSV (HSV-1 and HSV-2) infection (1,3,4).…”