Heroingestützte Therapie für Opiatabhängige - 
			 weder Allheilmittel noch Teufelswerk

Rehm, Jürgen; Fischer, Benedikt

doi:10.1055/s-2000-15607

Cited by 7 publications

(2 citation statements)

References 14 publications

(20 reference statements)

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“…Even though the introduction of this program was initially controversial [2,3], it is now an accepted therapeutic option among the wide variety of drug therapy programs in Switzerland [4]. The treatment goal was to reach long-term opioid addicts who so far could not be integrated into other treatment programs with an ambulant treatment program.…”

Section: Introductionmentioning

confidence: 99%

Evaluating Long-Term Effects of Heroin-Assisted Treatment: The Results of a 6-Year Follow-Up

et al. 2003

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Since January 1994, heroin-assisted treatment for opiate addicts has been available in Switzerland. This is the first report of the long-term effects of this form of treatment. The report examines subjects who entered a study involving medical prescription of opiates (Projekt zur ärztlichen Verschreibung von Betäubungsmitteln; PROVE) in Switzerland between January 1994 and March 1995 (n = 366). Opiates were dispensed in eight treatment centres. A follow-up was conducted 6 years after treatment entry. Two groups were assessed: clients who have continuously been on heroin-assisted treatment since entry into the PROVE study or who re-entered this treatment, and ex-clients who had discontinued heroin-assisted treatment at the time of follow-up. Two kinds of comparisons were conducted. Firstly, conditions at treatment entry were compared to 6-year follow-up outcomes, and secondly, outcomes were compared between clients still on heroin-assisted treatment and those who had been discharged. It was found that 46% of the clients still alive were on heroin-assisted treatment at the time of follow-up. A comparison of the present living conditions showed very little difference between those in treatment and those who had terminated treatment. Compared to the situation at entry, the results of the follow-up showed a significant decrease in the use of illegal substances, illegal income and most other variables concerning social conditions, but they also showed an increase in unemployment and reliance on social benefits. Heroin-assisted treatment is thus efficacious in the long-term course of treatment and is still effective after termination of treatment with respect to living conditions and use of illicit substances. AbstractSince January 1994, heroin-assisted treatment for opiate addicts has been available in Switzerland. This is the first report of the long-term effects of this form of treatment. The report examines subjects who entered a study involving medical prescription of opiates (Projekt zur ärztlichen Verschreibung von Betäubungsmitteln; PROVE) in Switzerland between January 1994 and March 1995 (n = 366). Opiates were dispensed in eight treatment centres. A follow-up was conducted 6 years after treatment entry. Two groups were assessed: clients who have continuously been on heroin-assisted treatment since entry into the PROVE study or who re-entered this treatment, and ex-clients who had discontinued heroin-assisted treatment at the time of follow-up. Two kinds of comparisons were conducted. Firstly, conditions at treatment entry were compared to 6-year follow-up outcomes, and secondly, outcomes were compared between clients still on heroin-assisted treatment and those who had been discharged. It was found that 46% of the clients still alive were on heroin-assisted treatment at the time of follow-up. A comparison of the present living conditions showed very little difference between those in treatment and those who had terminated treatment. Compared to the situation at entry, the results of the follow-up ...

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Section: Introductionmentioning

confidence: 99%

Evaluating Long-Term Effects of Heroin-Assisted Treatment: The Results of a 6-Year Follow-Up

et al. 2003

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“…40 Although this might be a desirable goal for science, it should be noted that heroin addiction and its consequences occur in distinct real-life environments (including unique cultural and system factors), and interventions need to be devised, measured, and evaluated within these to have authentic relevance for policy and practice. 33,41 Second, the discussed studies above have demonstrated in several different contexts that the implementation of HAT is feasible, effective, and safe as a therapeutic intervention. 21,24,26,30 This should not be seen as a conclusion that could be taken for granted because many observers expected disastrous consequences from the provision of medical heroin prescription.…”

Section: Discussionmentioning

confidence: 99%

Heroin-assisted Treatment (HAT) a Decade Later: A Brief Update on Science and Politics

Fischer

Oviedo‐Joekes

Blanken³

et al. 2007

J Urban Health

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111

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Since the initial Swiss heroin-assisted treatment (HAT) study conducted in the mid-1990s, several other jurisdictions in Europe and North America have implemented HAT trials. All of these studies embrace the same goal-investigating the utility of medical heroin prescribing for problematic opioid users-yet are distinct in various key details. This paper briefly reviews (initiated or completed) studies and their main parameters, including primary research objectives, design, target populations, outcome measures, current status and-where available-key results. We conclude this overview with some final observations on a decade of intensive HAT research in the jurisdictions examined, including the suggestion that there is a mounting onus on the realm of politics to translate the-largely positive-data from completed HAT science into corresponding policy and programming in order to expand effective treatment options for the high-risk population of illicit opioid users.

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Feasibility, safety, and efficacy of injectable heroin prescription for refractory opioid addicts: a follow-up study

Rehm¹,

Gschwend²,

Steffen³

et al. 2001

The Lancet

205

101

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Heroingestützte Therapie für Opiatabhängige - weder Allheilmittel noch Teufelswerk

Cited by 7 publications

References 14 publications

Evaluating Long-Term Effects of Heroin-Assisted Treatment: The Results of a 6-Year Follow-Up

Evaluating Long-Term Effects of Heroin-Assisted Treatment: The Results of a 6-Year Follow-Up

Heroin-assisted Treatment (HAT) a Decade Later: A Brief Update on Science and Politics

Feasibility, safety, and efficacy of injectable heroin prescription for refractory opioid addicts: a follow-up study

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