Hernia repair: the search for ideal meshes

Bringman, Sven; Conze, Joachim; Cuccurullo, Diego; Deprest, Jan; Junge, K.; Klosterhalfen, B.; Parra-Dávila, Eduardo; Ramshaw, Bruce; Schumpelick, Volker

doi:10.1007/s10029-009-0587-x

Cited by 186 publications

(142 citation statements)

References 26 publications

(34 reference statements)

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“…Currently utilized PP meshes are divided into 2 categories: heavy-weight and light-weight; however, a strict distinction is problematic [8]. At first, the breakdown criterion was the weight.…”

Section: Polypropylene Implantsmentioning

confidence: 99%

Synthetic Implants in Hernia Surgery

Łukasiewicz¹,

Drewa²

2014

Adv Clin Exp Med

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Abdominal wall hernia correction is one of the most common surgical procedures. 85,000 hernia operations are performed in Poland each year. Modern techniques of abdominal wall reconstruction utilize surgical implants for fascial defect closure. In the 70s and the 80s of the last century, these techniques gained widespread acceptance among surgeons. Significant improvement of results in terms of recurrences was observed. Treatment of large abdominal wall defects became possible. Three types of surgical implants were developed early: polipropylene (PP), poliethylene (PE) and politetrafluoroethylene (PTfE). Unfortunately, negative effects of implanted material soon became apparent. Excessive native tissues inflammatory response to the implanted material, leading to multiple complications was observed. Recurrences due to fibrosis, chronic regional pain, stiffness of the operation site, intestinal adhesions and fistulas, infertility and infections were reported. In some cases the use of standard synthetic implant was contraindicated. Analyzing drawbacks of the standard hernia implants, the medical industry developed new materials to improve treatment results. The most popular, currently utilized synthetic materials, are presented in this review in the context of clinical results (Adv Clin Exp Med 2014, 23, 1, 135-142).

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Section: Polypropylene Implantsmentioning

confidence: 99%

Synthetic Implants in Hernia Surgery

Łukasiewicz¹,

Drewa²

2014

Adv Clin Exp Med

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“…The ideal hernia mesh should be lightweight and flexible to reduce pain and foreign body sensation, as well as maintaining sufficient strength and durability to bridge fascial defects with minimal risk of recurrent hernia [1]. Through careful design, electrospun nanofiber meshes can balance these contradictory mechanical properties and provide a compromise between the mechanical stability of macrofiber meshes and the biocompatibility of biologically derived meshes.…”

Section: Discussionmentioning

confidence: 99%

“…In order to be considered sufficient for use in hernia repair applications, a mesh must have a minimum BBS of 50 N/cm, SRS [1,4,14]. Based on the statistical analyses, every mesh tested met or surpassed the 50 N/cm BBS threshold except PET.…”

Section: Discussionmentioning

confidence: 99%

“…The RS of PLLA was also comparable to that of MotifMESHTM. Mesh stiffness is an important factor to consider because a mesh that is too stiff may restrict the patient's range of motion in the abdominal region, causing discomfort, while a mesh that is too flexible may be difficult for surgeons to handle during the hernia repair procedure [1]. Although no universal radial stiffness standards or testing procedures have been established by the medical community at this time, the fact that the stiffness of PLLA is nearly equal to that of MotifMESHTM, a commercial surgical mesh approved by the FDA, is encouraging.…”

Section: Discussionmentioning

confidence: 99%

“…Synthetic polypropylene mesh was first used for hernia repair in 1958 [1,2]. Surgical mesh was a significant improvement over suture-based methods due to the ability of the mesh to close defects and support the surrounding abdominal wall tissue [3].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Development and Characterization of Novel Electrospun Meshes for Hernia Repair

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Surgical Materials

Hunt¹,

Chen²,

Williams³

et al. 2012

Ullmann's Encyclopedia of Industrial Chemistry

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This article contains sections titled: 1. Introduction 2. Surgical Applications of Materials 2.1. General Principles 2.2. Orthopedic Surgery 2.2.1. Bone and Joint Replacement 2.2.2. Ligament Augmentation and Repair 2.2.3. Fracture Fixation 2.3. Maxillofacial Surgery 2.3.1. Dental Implants 2.3.2. Maxillofacial and Orthognathic Surgery 2.4. Cardiovascular Surgery 2.4.1. Heart Valves 2.4.2. Vascular Prostheses 2.4.3. Cardiac Pacemakers 2.4.4. Extracorporeal Circuits 2.5. Ophthalmology 2.5.1. Corneal Replacement 2.5.2. Intraocular Lenses 2.5.3. Contact Lenses 2.5.4. Vitreoretinal Surgery 2.6. Neurosurgery 2.6.1. Nerve Repair and Regeneration 2.6.2. Neuromodulation: Nerve Stimulators 2.6.3. Treatment of Hearing Loss 2.7. General Surgery 2.7.1. Wound Closure and Artificial Skin 2.7.2. Soft Tissue Reconstruction: Plastic Surgery 2.7.3. Soft Tissue Repair: Hernia and Pelvic Floor Repair 2.7.4. Surgery of the Urinary Tract 2.8. Artificial Organs 3. Criteria for Materials Selection 3.1. Mechanical and Physical Properties 3.1.1. Mechanical Performance 3.1.2. Electrical and Optical Properties 3.2. Manufacturing and Sterilization 3.2.1. Constraints on Fabrication 3.2.2. Market Analyses 3.2.3. Legal and Regulatory Constraints 3.2.4. Sterilization Techniques 3.3. Biocompatibility 3.3.1. General Principles 3.3.2. Corrosion and Degradation 3.3.3. Soft Tissue Biocompatibility 3.3.4. Hard Tissue Biocompatibility 3.3.5. Blood Compatibility 3.3.6. Systemic Biocompatibility 3.3.7. Genotoxicity and Carcinogenicity 3.3.8. Bioactivity 4. Materials 4.1. Metals and Alloys 4.2. Ceramics and Glasses 4.3. Polymers 4.4. Carbon 4.5. Composites 4.6. Surface Modifications and Coatings

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Hernia repair: the search for ideal meshes

Cited by 186 publications

References 26 publications

Synthetic Implants in Hernia Surgery

Synthetic Implants in Hernia Surgery

Development and Characterization of Novel Electrospun Meshes for Hernia Repair

Surgical Materials

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