Hernia diafragmática congénita: criterios pronósticos y estado actual del tratamiento prenatal. Guía clínica

García-Posada, Raúl Alejandro; Gómez, O.; Martínez, Josep M.; Puerto, B.; Gratacós, E.

doi:10.1016/j.diapre.2012.06.009

Cited by 4 publications

(2 citation statements)

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“…The right lung-to-head ratio (LHR) was calculated for each fetus by two independent specialists per ultrasound as described by Metkus et al by multiplication of the longest diameter of the lung by its longest perpendicular diameter ( 9 ). The expected LHR was then calculated as described by Posada et al ( 17 ) and the O/E LHR was calculated as Observed LHR/Expected LHR × 100. Primary endpoint of the study was development of respiratory distress with need for respiratory support in the delivery room.…”

Section: Methodsmentioning

confidence: 99%

Observed to expected lung area to head circumference ratio (O/E LHR) in fetuses with congenital anomalies of the kidney and urinary tract (CAKUT): assessment and evaluation as predictive factor for acute postnatal outcome—a single center study

Sourouni,

Haisch,

Oelmeier

et al. 2023

Front. Pediatr.

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IntroductionTo assess the observed to expected lung area to head circumference ratio (O/E LHR) in fetuses with congenital anomalies of the kidney and urinary tract (CAKUT) and to explore its value as a potential predictive factor for postnatal outcome.MethodsA retrospective single-center study was conducted on pregnancies complicated by CAKUT between 2007 and 2018. The lung-to-head ratio (LHR) was calculated for each fetus by two independent observers. Correlations between O/E LHR and various perinatal outcome factors were assessed with Spearman's rank correlation. Furthermore, nominal logistic regression was performed to assess O/E LHR as predictive factor for respiratory distress in newborn.ResultsOf 64 pregnancies complicated by CAKUT, 23 were terminated. In the 41 cases of continuation of pregnancy, newborn presenting respiratory distress with need for respiratory support in the delivery room showed earlier gestational age at onset of amniotic fluid abnormalities and at birth. Although median O/E LHR and median single deepest pocket (SDP) of amniotic fluid were significantly smaller in newborn that did develop respiratory distress with need of respiratory support in the delivery room, neither O/E LHR nor SDP were accurate predictors for the development of respiratory distress.ConclusionsOur data show that O/E LHR alone cannot serve as a predictive marker for fetal outcome in pregnancies complicated by CAKUT, though it might still be a helpful parameter together with detailed renal ultrasound evaluation, onset of amniotic fluid abnormality and SDP, particularly in its extreme values.

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Section: Methodsmentioning

confidence: 99%

Observed to expected lung area to head circumference ratio (O/E LHR) in fetuses with congenital anomalies of the kidney and urinary tract (CAKUT): assessment and evaluation as predictive factor for acute postnatal outcome—a single center study

Sourouni,

Haisch,

Oelmeier

et al. 2023

Front. Pediatr.

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show abstract

“…Con este método, a la semana 24 se diagnostican del 50 al 70% de los casos. 11,12 La autopsia (o estudio post mortem) es un procedimiento invaluable, al brindar hallazgos histopatológicos certeros y con información morfológica de alta calidad, tanto de los órganos involucrados como de las malformaciones acompañantes en otros sitios anatómicos. 11 Este procedimiento en niños con HDC puede ser muy relevante ya que es posible integrar síndromes genéticos o determinar si la malformación fue aislada.…”

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