Hermann Michael Biggs and tuberculosis as a public health concern

Tm, Daniel

doi:10.5588/ijtld.08.0472

Cited by 6 publications

(1 citation statement)

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“…The decision to build a sanatorium in a non-mountainous area was motivated by the desire to keep patients in their habitual climatic environment. This meant that patients could be supported and assisted more easily by their family members and maintain their daily habits – factors deemed conducive to achieving a more stable “cure” than would be possible if the patient were transferred to a mountain environment [ 15 ].…”

Section: The Fight Against Tuberculosis In Italy At the Beginning Of mentioning

confidence: 99%

The History of Tuberculosis: The Social Role of Sanatoria for the Treatment of Tuberculosis in Italy Between the End of the 19th Century and the Middle of the 20th

Martini

Gazzaniga

Behzadifar

et al. 2018

Journal of Preventive Medicine and Hygiene

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Section: The Fight Against Tuberculosis In Italy At the Beginning Of mentioning

confidence: 99%

The History of Tuberculosis: The Social Role of Sanatoria for the Treatment of Tuberculosis in Italy Between the End of the 19th Century and the Middle of the 20th

Martini

Gazzaniga

Behzadifar

et al. 2018

Journal of Preventive Medicine and Hygiene

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Tuberculosis

Bhatt¹,

Gour²,

Singh³

et al. 2020

Chronic Lung Diseases

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Treatment of Tuberculosis. A Historical Perspective

2015

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Of all achievements in medicine, the successful treatment of tuberculosis has had one of the greatest impacts on society. Tuberculosis was a leading cause of disease and a mortal enemy of humanity for millennia. The first step in finding a cure was the discovery of the cause of tuberculosis by Robert Koch in 1882. The sanatorium movement that began shortly afterward in Europe, and soon spread to the United States, brought attention to the plight of afflicted persons, and catalyzed public health action. The antituberculosis benefit of streptomycin was announced in 1945, although application was limited by the rapid development of resistance. para-Aminosalicylic acid, also discovered in 1945, when combined with streptomycin was found to greatly reduce the occurrence of drug resistance. In 1952, isoniazid opened the modern era of treatment; it was inexpensive, well tolerated, and safe. In the early 1960s, ethambutol was shown to be effective and better tolerated than para-aminosalicylic acid, which it replaced. In the 1970s, rifampin found its place as a keystone in the therapy of tuberculosis. The use of rifampin enabled the course of treatment to be reduced to nine months. Incorporation of pyrazinamide into the first-line regimen led to a further reduction of treatment duration to six months. Treatment of multiple drug-resistant tuberculosis remains a difficult problem requiring lengthy treatment with toxic drugs. However, shortened regimens show promise, and two new drugs, bedaquiline and delamanid, have demonstrated effectiveness in preliminary studies and are being used for extensively drug-resistant tuberculosis.

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Hermann Michael Biggs and tuberculosis as a public health concern

Cited by 6 publications

References 0 publications

The History of Tuberculosis: The Social Role of Sanatoria for the Treatment of Tuberculosis in Italy Between the End of the 19th Century and the Middle of the 20th

The History of Tuberculosis: The Social Role of Sanatoria for the Treatment of Tuberculosis in Italy Between the End of the 19th Century and the Middle of the 20th

Tuberculosis

Treatment of Tuberculosis. A Historical Perspective

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