Hereditary Thyroglossal Duct Cysts

Outcome of thyroglossal duct cyst excision is independent of presenting age or symptomatology

“…A larger population is necessary to determine the true incidence. It is important to note, however, that it has been suggested that a true female predominance does exist amongst familial thyroglossal duct cysts [3].…”

“…Despite the relative frequency of TGDCs, familial occurrences are rare. The inheritance pattern is usually autosomal dominant with incomplete penetrance, and a female preponderance has been noted [3].…”

Thyroglossal duct cysts: presentation and management in children versus adults

“…However, a female predominance and some pattern of autosomal dominance have been observed [15]. It has also been suggested that the female predominance may be due to genetic imprinting, but there is no data supporting this theory at this time [15]. There may be a higher incidence of familial TGDC than that currently reported in the literature.…”

“…There have been few reports of familial occurrence none of which described a clear pattern of inheritance [13][14][15][16][17][18]. However, a female predominance and some pattern of autosomal dominance have been observed [15].…”

Thyroglossal Duct Cysts

“…There is minimal gender difference, occurring equally in male and female populations [5,9]. TGDC occur sporadically within the population and despite reports of occurrence in multiple members of some families, they do not appear to have any genetic pattern of inheritance [10].…”