Hereditary Hemorrhagic Telangiectasia

Pancreatic Arteriovenous Malformation

“…This autosomal-dominant syndrome is characterized by recurrent epistaxis, telangectasia of the skin, intra-abdominal arteriovenous malformations and a familial history [6, 7]. …”

Hepatic angiography in hereditary hemorrhagic telangiectasia

“…Halpern et al [6] have summarized the major abdominal findings to include congenital visceral aneurysm, direct arteriovenous and arteriocapillary-venous shunting in the bowel and liver, local phlebectasia, and discrete angiomata. All of our cases demonstrated uniformly dilated and tortuous hepatic arteries, a moderately dense, slightly mottled hepatogram, and early but no immediate hepatic vein opacification.…”

“…One important point which emerges from the two cases who were subjected to open liver biopsy was the unimpressive histology in this condition in contrast to the dramatic angiogram. Unless extensive cirrhosis is present, the only significant finding may well be the presence of slightly ectatic vascular channels [6]. Stains for elastic tissue may reveal its deficiency in the walls of the vessels.…”

Solitary angiodysplastic lesions in the ileocaecal region diagnosed by angiography

“…Although bleeding is the commonest clinical presentation, the angiodysplasia may be a mass lesion and cause obstruction (Bailey, Barrick, and Jenkinson, 1956) or, especially in the small bowel, result in intussusception (Weinstein, Moertel, and Waugh, 1963). The presence of angiodysplastic lesions on the skin or mucous membranes may be associated with similar lesions in the gastrointestinal tract (Halpern et al, 1968). The lesion is discovered at operation in about half the cases, but is often an incidental necropsy finding.…”

“…Although there may be a tendency for enlargement (Packard, 1945), the lesions Received for publication 29 August 1973. are now generally regarded as being congenital (Shepherd, 1953). The term 'angiodysplasia' is used to encompass these vascular abnormalities and also stresses their congenital nature (Halpern, Turner, and Citron, 1968).…”