Hereditary haemorrhagic telangiectasia, an <scp>A</scp>ustralian cohort: clinical and investigative features

Salaria, M; Taylor, Jessica Averitt; Bogwitz, Michael; Winship, Ingrid

doi:10.1111/imj.12457

Cited by 13 publications

(11 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hereditary haemorrhagic telangiectasia is a rare genetically heterogeneous disease with autosomal dominant inheritance characterized by vascular malformations in mucocutaneous tissues, internal organs and the central nervous system …”

Section: Treatment Of Different Vascular Lesionsmentioning

confidence: 99%

Guidelines of care for vascular lasers and intense pulse light sources from the European Society for Laser Dermatology

Adamič¹,

Pavlović

Rubin

et al. 2015

Acad Dermatol Venereol

View full text Add to dashboard Cite

Aim Lasers and non-coherent intense pulse light sources (IPLS) are based on the principle of selective photothermolysis and can be used for the treatment of many vascular skin lesions. A variety of lasers has been developed for the treatment of congenital and acquired vascular lesions which incorporate these concepts into their design. Although laser and light sources are very popular due to their non-invasive nature, caution should be considered by practitioners and patients to avoid permanent side-effects. The aim of these guidelines is to give evidence-based recommendations for the use of lasers and IPLS in the treatment of vascular lesions. Results Lasers and IPLS are very useful and sometimes the only available method to treat various vascular lesions. It is of a paramount importance that the type of laser or IPLS and their specific parameters are adapted to the indication but also that the treating physician is familiar with the device to be used. The crucial issue in treating vascular lesions is to recognize the immediate end-point after laser treatment. This is the single most important factor to ensure both the efficacy of the treatment and avoidance of serious side-effects. Methods Conflicts of interestNone declared. Funding sourceNone.Since the publication of previous European Society of Laser Dermatology (ESLD) guidelines in 2007, there have been significant advances in the field of laser treatment of common vascular lesions.1 These guidelines have been updated by the Consensus Panel under the auspices of the ESLD. Methodology, search strategy and recommendation formulation are described in Appendix II. A brief overview of vascular lasersStandard vascular lasers include pulsed dye lasers (585 and 595 nm), and KTP-lasers (532 nm), followed by longer wavelength lasers such as alexandrite lasers (755 nm), diode lasers (800-900 nm) and millisecond Nd:YAG lasers (1064 nm). New developments include a non-uniform pulse sequence or a dual-wavelength modality (combined dual wavelength 595 and 1064 nm-pulsed dye and Nd:YAG laser) and microsecond Nd: YAG lasers. [2][3][4][5][6] Even fractional photothermolysis has begun to be used for selected vascular lesions. Lasers' and intense pulse light sources (IPLS) effects are based on the principle of selective photothermolysis. In general, they deliver a precisely graded aliquot of energy to a defined area of the skin in a reproducible, standardized manner that almost always involves addition or evacuation of heat. The greatestThe first two authors have contributed equally to the manuscript.

show abstract

Section: Treatment Of Different Vascular Lesionsmentioning

confidence: 99%

Guidelines of care for vascular lasers and intense pulse light sources from the European Society for Laser Dermatology

Adamič¹,

Pavlović

Rubin

et al. 2015

Acad Dermatol Venereol

View full text Add to dashboard Cite

show abstract

“…We read with interest the study by Salaria et al 1 In this retrospective audit, 52 patients who had a definite diagnosis of hereditary haemorrhagic telangiectasia (HHT) as per Curacao criteria were identified, and 21 of these patients had a genetic diagnosis. The most common features found in this study were epistaxis (93%), telangectasia (95%), pulmonary arteriovenous malformations (AVM) (46%), hepatic AVM (71%) and cerebral AVM (16%).…”

mentioning

confidence: 99%

Cerebral screening in patients with hereditary haemorrhagic telangiectasia

Jackson¹,

Briggs

Clayton‐Smith

2014

Internal Medicine Journal

View full text Add to dashboard Cite

“…6 It is difficult to reconcile the absence of renal involvement in HHT with the high vascularity of the kidney and the high prevalence of extra-renal internal lesions. 6 It is difficult to reconcile the absence of renal involvement in HHT with the high vascularity of the kidney and the high prevalence of extra-renal internal lesions.…”

Section: Discussionmentioning

confidence: 99%

“…6 Sequential patients were invited to participate if they met inclusion criteria. 6 Sequential patients were invited to participate if they met inclusion criteria.…”

mentioning

confidence: 99%

Absence of renal phenotype in hereditary haemorrhagic telangiectasia

Healy

Nicholls

Gibson

et al. 2018

Internal Medicine Journal

View full text Add to dashboard Cite

Hereditary haemorrhagic telangiectasia is characterised by abnormal blood vessel formation, producing telangiectasia and arteriovenous malformations in multiple organs. Information regarding possible renal involvement in hereditary haemorrhagic telangiectasia is limited. This study assessed renal structure and function in 11 patients with genetically confirmed diagnosis and known arteriovenous malformations in lung, liver, gastrointestinal tract or brain. All had significant current or past epistaxis. Despite the vascularity of the kidneys, we found no evidence of renal involvement. This observation warrants further consideration.

show abstract

Hereditary haemorrhagic telangiectasia, an Australian cohort: clinical and investigative features

Abstract: HHT is a multisystemic disorder and needs involvement of a team with experience in managing patients with HHT.

Cited by 13 publications

References 26 publications

Guidelines of care for vascular lasers and intense pulse light sources from the European Society for Laser Dermatology

Guidelines of care for vascular lasers and intense pulse light sources from the European Society for Laser Dermatology

Cerebral screening in patients with hereditary haemorrhagic telangiectasia

Absence of renal phenotype in hereditary haemorrhagic telangiectasia

Contact Info

Product

Resources

About