Hereditary Angioedema and Hormones

Treatment of hereditary angioneurotic oedema (HANE) with tibolone

“…HANE appears, at least in part, to be hormonally dependent, with women generally having a more severe course of the disease than men 2,10,11 . Production of C1‐INH by hepatocytes is reported to be stimulated by androgens and inhibited by oestrogens 4,12,13 .…”