Hereditary Angioedema

Abstract

The authors present the case of a 22-year-old female who reported having a persistent sore throat. The patient had a history of recurring episodes of hereditary angioedema and arrived at the emergency department with her C1-esterase inhibitor. The epidemiology, clinical presentation, and treatment strategies are presented.

Navigating the swells: A case report of hereditary angioedema

“…[ 1 ] It is caused by a deficiency or dysfunction of C1 inhibitor (C1-INH), a regulatory protein involved in controlling the complement and coagulation systems. [ 2 ] The condition leads to uncontrolled activation of bradykinin, resulting in increased vascular permeability and angioedema formation. [ 3 ] HAE affects approximately 1 in 50,000 individuals worldwide[ 4 ] and can manifest at any age, with onset typically occurring during childhood or adolescence.…”