Hereditary and multivariate connective tissue disorders in children Algorithm of diagnosis. Management tactics

Кадурина, Т И; Гнусаев, С. Ф.

doi:10.14300/mnnc.2015.10001

Cited by 13 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…В ряду методов физиотерапии особая роль отводится сочетанным мето-дам водолечения -одним из самых физиологичных и, одновременно, эффективных немедикаментозных спо-собов реабилитации детей с частыми и затяжными ОРИ [9,10]. Существует ограниченное число качественных научных исследований по их применению у таких паци-ентов [10,14,21]. На этом фоне однонаправленные результаты, полученные в ходе описанных исследований, позволяют расширить спектр применяемых в педиатрии оздоровительных технологий.…”

Section: Discussionunclassified

“…По данным научных исследований, проведенных в 2001 г. в Российском научном центре восстановитель-ной медицины и курортологии, у 25 детей в возрасте 4-15 лет из группы часто и длительно болеющих ОРИ с начальными признаками острой респираторной инфек-ции была выявлена высокая эффективность примене-ния концентрата для противопростудных ванн на основе эфирных масел эвкалипта, ментола и камфоры [14]. Про тивовоспалительный эффект указанных ванн харак-теризовался быстрой положительной динамикой со сто-роны основных клинических симптомов респираторной инфекции у 68,0% пациентов.…”

Section: натуральные эфирные маслаunclassified

“…Аналогичное обследование пациентов груп-пы сравнения (получавших пресные ванны) не выявило достоверной динамики показателей. Совокупные данные этого исследования позволили сделать вывод о повы-шении степени иммунологической защиты под влиянием бальнеотерапевтического курса с использованием аро-мафитоконцентрата для противопростудных ванн [9,14].…”

Section: натуральные эфирные маслаunclassified

See 2 more Smart Citations

Aromaphytobalneotherapy in Treatment and Prophylaxis of Frequent Respiratory Infections in Children with Chronic and Disabling Diseases

Конова¹,

Дмитриенко²,

Dmitrienko³

et al. 2016

Pediatr. farmakol.

View full text Add to dashboard Cite

Section: Discussionunclassified

Section: натуральные эфирные маслаunclassified

See 1 more Smart Citation

Aromaphytobalneotherapy in Treatment and Prophylaxis of Frequent Respiratory Infections in Children with Chronic and Disabling Diseases

Конова¹,

Дмитриенко²,

Dmitrienko³

et al. 2016

Pediatr. farmakol.

View full text Add to dashboard Cite

“…Фены дисплазии манифестируют в течение жизни: у новорожденных выявление признаков минимально. Проявление фенотипических признаков имеет прогредиентность: в возрасте 4-5 лет манифестируют пролапсы клапанов, в 5-7 лет -воронкообразная и килевидная грудная клетка, деформация позвоночного столба, патология стопы, миопия, в подростковом возрасте -геморрагический синдром 2 [7][8][9][10], что связано с периодами усиленного роста, т. н. ростовыми скачками. Критическим периодом является подростковый, что связано с максимальным напряжением всех систем организма и увеличением общей массы соединительной ткани.…”

Section: школа педиатраunclassified

Structural features of the heart in children with arrhythmic syndrome due to nonspecific connective tissue disorder

Nechaeva,

Dakuko,

Loginova

et al. 2023

Medicinskij sovet

View full text Add to dashboard Cite

Introduction. Connective tissue is highly organized system, its disorders are characterized by a pronounced polymorphism of morphological and clinical manifestations. The cardiovascular pathology in patients with nonspecific connective tissue disorder attracts attention due to the high risk of complications: rhythm and conduction disorders, infective endocarditis, vascular thromboembolism and sudden cardiac death. Therefore, it’s very important to use up-to-date equipment and methods of early diagnosis of a high risk of fatal events in young.Aim. To investigate the structural features of the heart and their relationship with the process of myocardial remodeling in children with arrhythmic syndrome and nonspecific connective tissue disorder.Materials and methods. Sixty-five children were examined, 40 of them had arrhythmic syndrome in combination with nonspecific connective tissue disorder, and 25 had only minimal manifestations of nonspecific connective tissue disorder without arrhythmic syndrome. Such up-to-date methods as assessment of myocardial remodeling and longitudinal strain, natriuretic peptide assessment were included in the diagnostic algorithm.Results and discussion. The study showed a variety of phenotypic and visceral markers of nonspecific connective tissue disorder in children with arrhythmic syndrome. Arrhythmic syndrome was manifested by monotopic and heterotopic heart rhythm disorders, and structural changes of the heart: mitral valve prolapse and myocardial wall thinning were correlated with a more frequent increase in natriuretic peptide. Speckle-tracking echocardiography showed a significant decrease in longitudinal myocardial strain with predominance of myocardial strain in the anterior basal segment in children with arrhythmic syndrome.Conclusion. Our study showed a variety of phenotypic and visceral markers of undifferentiated connective tissue dysplasia in children with arrhythmic syndrome. The data obtained require further mathematical analysis and the establishment of a possible relationship between the external manifestations of the disease and cardiac rhythm and conduction disturbances.

show abstract

“…В этой связи раннее выявление ДСТ может иметь высокую практическую и социальную значимость. Имеющиеся в настоящее время критерии и алгоритмы диагностики ДСТ трудоемки, зачастую субъективны, что делает их малопригодными для скрининга и, соответственно, обусловливает существенную вариабельность данных по распространенности ДСТ у детей и подростков [2,5]. Результаты, полученные исследователями в разных регионах России с использованием различных методологических подходов, невозможно сопоставить между собой, при этом зачастую полученные сведения недостаточно полно отражают суть проблемы.…”

unclassified

The Incidence and Clinical Characteristics of the Connective Tissue Dysplasia in Adolescents

Калаева¹,

Хохлова²,

Деев³

et al. 2017

Pediatr. farmakol.

View full text Add to dashboard Cite

Early detection of the connective tissue dysplasia (CTD) is hampered as the used diagnostic criteria are complex and subjective. The aim of the study is to examine the incidence and clinical profile of the adolescent CTD by means of the screening checklist. Methods. The study included the pupils at the age of 10-14 years. The questionnaire designed to reveal the 7 CTD's signs (thin skin, skin hyperelasticity, keloid cicatrix, blue sclera, soft auricles, arachnodactylia, joints hypermobility), containing 12 illustrated questions with explanation for the parents, was performed as a screening method. The conditionally healthy group (the absence of CTD) consisted of the adolescents with below 12 points total and CTD group was presented by the adolescents with 13 and more points. The physical development was appreciated according to the centile tables, Quetelet index and Vargui index. The health status analysis was based on the outpatient medical records. Results. 1560 pupils were the participants of the study: 752 boys (48.2%) and 808 girls (51.8%). CTD signs were observed in 965 (61.9%) children. The adolescents with CTD's signs demonstrated the following characters more often than the adolescents without CTD's signs: soft auricles-788 (81.7%) against 277 (46.6%), skin hyperelasticity-685 (71%) against 93 (15.6%), joints hypermobility-665 (68.9%) against 203 (34.1%), blue sclera-665 (68.9%) against 184 (30.9%), arachnodactylia-534 (55.3%) against 57 (9.6%). The disharmonious physical development because of the underweight body took place in 430 (52.3%) adolescents with CTD. Compared to the conditionally healthy group the most of the adolescents with CTD had the pathology of the musculoskeletal system (scoliosis, flatfoot), myopia, vegetative-vascular dystonia, digestive apparatus diseases. The CTD is associated with greater probability of the development of above mentioned pathologies, that can be indicative of the contribution of the anomalies of the connective tissue development into the etiopathogenesis of the these diseases. Conclusion. It is established that there is the high prevalence of the CTD signs among the adolescents (pupils) at the age of 10-14 years.

show abstract

Hereditary and multivariate connective tissue disorders in children Algorithm of diagnosis. Management tactics

Cited by 13 publications

References 0 publications

Aromaphytobalneotherapy in Treatment and Prophylaxis of Frequent Respiratory Infections in Children with Chronic and Disabling Diseases

Aromaphytobalneotherapy in Treatment and Prophylaxis of Frequent Respiratory Infections in Children with Chronic and Disabling Diseases

Structural features of the heart in children with arrhythmic syndrome due to nonspecific connective tissue disorder

The Incidence and Clinical Characteristics of the Connective Tissue Dysplasia in Adolescents

Contact Info

Product

Resources

About