Herbicide Safeners: Effective Tools to Improve Herbicide Selectivity

Jablonkai, István

doi:10.5772/55168

Cited by 35 publications

(57 citation statements)

References 82 publications

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“…The results in this study showed that the GSH content, GST activity in vivo, and ALS activity were increased by safeners treatment under laboratory condition, which is in agreement with previous studies (Jablonkai, 2013). Without imazethapyr application, seed treatment with these safeners also promoted the increase of GST activity in vitro and affinity of GST enzyme.…”

Section: Als Activitysupporting

confidence: 81%

“…In 1947, Hoffman realized that safener was a useful tool to protect crop from herbicide injury. Nearly 20 safeners has subsequently been developed and commercialized by famous agrochemical companies (Jablonkai, 2013). While the exact mechanism of safener is still not completely understood, it seems that safeners could increase crop tolerance by inducing the activity of detoxifying enzyme glutathione S-transferases (GST) and content of glutathione (GSH) involved in detoxification of exogenous compounds (Del Buono and Ioli, 2011;Matola and Jablonkai, 2007).…”

Section: Introductionmentioning

confidence: 99%

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3-Dichloroacetyl oxazolidine protect maize from imazethapyr herbicide injury

Zhao

et al. 2016

Chilean J. Agric. Res.

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Safeners are an important tool used to ensure the safe using of herbicide. The objective of this paper was to investigate the protective effect of four 3-dichloroacetyl oxazolidine safeners (3-dichloroacetyl-2,2-dimethyl-1,3-oxazolidine [R-28725], racemate of 3-dichloroacetyl-2,2-dimethyl-4-ethyl-1,3-oxazolidine, and its two chiral stereoisomers) in reducing the injury caused by imazethapyr. Physiological and biochemical tests were conducted under laboratory condition, by using seed treatment with safeners and soil treatment with imazethapyr, respectively. The interaction of two safeners (R-28725 and R-stereoisomer) and imazethapyr reduced the injury of maize significantly, and also increased glutathione content, activity of glutathione S-transferases, and activity of acetolactate synthase in maize. When induced by R-stereoisomer, the GSH content in root and in shoot increased 100.7% and 73.6%, respectively. When induced by R-28725, the GST activity in vivo increased threefold and the GST activity in vitro more than doubled. The kinetic parameter Vmax of GST in the maize treated with R-28725 and R-stereoisomer increased by 102.2% and 81.9%, respectively, compared with the control. The results also showed that R-28725 and R-stereoisomer induced glutathione S-transferases affinity for the substrate of conjugation reaction significantly.

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Section: Als Activitysupporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

3-Dichloroacetyl oxazolidine protect maize from imazethapyr herbicide injury

Zhao

et al. 2016

Chilean J. Agric. Res.

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“…As response to treatment with safener, the content of GSH in maize increased significantly. The increase of GSH induced by safener has also been reported previously (Jablonkai, 2013). …”

mentioning

confidence: 53%

“…In the late 1940s, the phenomenon of herbicide safener was discovered serendipitously by Otto Hoffman. The products of safener were subsequently commercialized by agrochemical companies intensively in late 20 th century (Jablonkai, 2013). Nevertheless intensive research has been conducted in recent years; the exact mechanism of safener is incompletely understood (Hull et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

The safener effect of chiral derivatives of 3-dichloroacetyl oxazolidine against haloxyfop-P-methyl-induced toxicity in maize

Fei

Cao

et al. 2016

Zemdirbyste-Agriculture

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Herbicide safener, a diverse group of chemicals, is an important tool used to protect plants from herbicidal injury. With the aim of decreasing drift injury of haloxyfop-P-methyl to sensitive plants, the protective effect of four safeners (R-28725, 3-dichloroacetyl oxazolidine and its two optical isomers) was evaluated. Physiological and biochemical tests were conducted under laboratory conditions in Northeast Agricultural University, China, by using seed treatment with safener and soil treatment with haloxyfop-P-methyl, respectively. The maize seeds treated with these safeners were safe from haloxyfop-P-methyl treatment. A positive correlation between growth level and endogenous glutathione (GSH) content, glutathione S-transferases (GST) activity was observed in this research. Enhancement of GSH content, GST activity and affinity of GST to 1-chloro-2,4-dinitrobenzene (CDNB) in maize treated by R-28725 was maximum. However, the detoxification of herbicide was not accompanied by the increase of acetyl-CoA-carboxylase (ACC) activity in maize.

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“…Most enzymatic reactions in plants are stereoselective; thus, the biological activity of the two optically active enantiomers of 3-dichloroacetyl-2,2-dimethyl-4-ethyl-1,3-oxazolidine and racemate could be different because of their chirality (Kang et al 2005;Sriharsha and Shashikanth 2006). However, few studies have investigated the detoxification mechanisms of chiral safener (Jablonkai 2013). In previous studies, we have synthesized chiral 3-dichloroacetyl-substituted oxazolidines successfully and investigated their bioactivity as safeners of chlorsulfuron (Zhao et al 2012(Zhao et al , 2014.…”

mentioning

confidence: 99%

Alleviation of injury from chlorimuron-ethyl in maize treated with safener 3-dichloroacetyl oxazolidine

ZhaoLi-Xia¹,

QuHai-Tao²,

FuYing³

et al. 2015

Can. J. Plant Sci.

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. 2015. Alleviation of injury from chlorimuron-ethyl in maize treated with safener 3-dichloroacetyl oxazolidine. Can. J. Plant Sci. 95: 897Á903. The protective effects of herbicide safeners, including 3-dichloroacetyl-2,2-dimethyl-1,3-oxazolidine (R-28725), 3-dichloroacetyl-2,2-dimethyl-4-ethyl-1,3-oxazolidine (Racemate), and its two enantiomers (R)-3-dichloroacetyl-2,2-dimethyl-4-ethyl-1,3-oxazolidine (R-enantiomer) and (S)-3-dichloroacetyl-2,2-dimethyl-4-ethyl-1,3-oxazolidine (S-enantiomer), on reducing the phytotoxicity of chlorimuronethyl to maize were investigated. Soaking the seeds in safeners increased the endogenous glutathione (GSH) content and glutathione-S-transferase (GST) activity of maize. When induced by R-enantiomer, the GST activity in vivo and in vitro increased 180 and 192% compared with control, respectively. R-28725 and R-enantiomer also increased the acetolactate synthase (ALS) activity inhibited by chlorimuron-ethyl from 45 to 100 and 97% compared with the control, respectively. The kinetic parameter V max of GST in the maize treated with R-28725 and R-enantiomer increased by 103 and 92%, respectively, compared with the control. Our results suggest that R-28725 and R-enantiomer could significantly improve the GSH content, GST activity, and ALS activity of maize. Overall, maize could be protected from the injury caused by chlorimuron-ethyl.Key words: Herbicide injury, safener, 3-dichloroacetyl oxazolidine Zhao, L.-X., Qu, H.-T., Fu, Y., Gao, S. et Ye, F. 2015. Atte´nuation des dommages re´sultant du chlorimuron Á e´thyle chez le maı¨s traite´avec le phytoprotecteur 3-dichloroace´tyl oxazolidine. Can. J. Plant Sci. 95: 897Á903. Les auteurs ont examineć omment divers phytoprotecteurs, notamment la 3-dichloroace´tyl-2,2-dime´thyl-1,3-oxazolidine (R-28725), la 3-dichloroace´tyl-2, 2-dime´thyl-4-e´thyl-1,3-oxazolidine (Racemate) et leurs isome`res optiques (R)-3-dichloroace´tyl-2,2-dime´thyl-4-e´thyl-1,3-oxazolidine (isome`re optique R) et (S)-3-dichloroace´tyl-2,2-dime´thyl-4-e´thyl-1,3-oxazolidine (isome`re optique S), atte´nuent la toxicite´du chlorimuronÁe´thyle pour le maı¨s. Tremper les semences dans le phytoprotecteur augmente la concentration de glutathion endoge`ne (GSH) et l'activite´de la glutathion-S-transfe´rase (GST) du maı¨s. L'isome`re optique R augmente respectivement l'activite´in vivo et in vitro de la GST de 180 % et de 192 % comparativement aux te´moins. Le R-28725 et son isome`re optique R accroissent aussi l'activite´de l'ace´tolactate synthe´tase (ALS) inhibe´e par le chlorimuronÁe´thyle de 45 % a`100 % et de 97 %, respectivement, par rapport aux te´moins. Chez le maı¨s traite´avec du R-28725 et son isome`re optique R, le parame`tre cine´tique V max de la GST augmente respectivement de 103 % e de 92 % comparativement aux te´moins. Ces re´sultats donnent a`penser que le R-28725 et son isome`re optique R pourraient sensiblement augmenter la teneur en GSH, l'activite´de la GST et l'activite´de l'ALS chez le maı¨s. Dans l'ensemble, le maı¨s serait ainsi prote´ge´contre les do...

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Herbicide Safeners: Effective Tools to Improve Herbicide Selectivity

Cited by 35 publications

References 82 publications

3-Dichloroacetyl oxazolidine protect maize from imazethapyr herbicide injury

3-Dichloroacetyl oxazolidine protect maize from imazethapyr herbicide injury

The safener effect of chiral derivatives of 3-dichloroacetyl oxazolidine against haloxyfop-P-methyl-induced toxicity in maize

Alleviation of injury from chlorimuron-ethyl in maize treated with safener 3-dichloroacetyl oxazolidine

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