Herbicide Metabolism as a Basis for Selectivity

Owen, W. J.

doi:10.1007/978-1-4899-2433-9_10

Cited by 24 publications

(20 citation statements)

References 106 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The physiological and genetic basis of resistance has not been determined, although it is not due to single gene, target-site resistance (Table 5). Species-dependent variations in the rate and mechanism of detoxification of some herbicides are the basis of herbicide selectivity (Owen, 2000). Indeed, grass weed control in wheat by some ACCase herbicides is based on differential rates of herbicide metabolism mediated by the cytochrome P450 and glutathione-S-transferase enzyme families (see Cole and Edwards, 2000).…”

Section: Discussionmentioning

confidence: 99%

High survival frequencies at low herbicide use rates in populations of Lolium rigidum result in rapid evolution of herbicide resistance

2005

View full text Add to dashboard Cite

The frequency of phenotypic resistance to herbicides in previously untreated weed populations and the herbicide dose applied to these populations are key determinants of the dynamics of selection for resistance. In total, 31 Lolium rigidum populations were collected from sites with no previous history of exposure to herbicides and where there was little probability of gene flow from adjacent resistant populations. The mean survival frequency across all 31 populations following two applications of commercial rates (375 g ha À1 ) of the acetyl-coenzyme A carboxylase (ACCase) inhibiting herbicide, diclofop-methyl was 0.43%. Survivors from five of these populations were grown to maturity and seed was collected. Dose-response experiments compared population level resistance to diclofop-methyl in these selected lines with their original parent populations. A single cycle of herbicide selection significantly increased resistance in all populations (LD 50 R:S ratios ranged from 2.8 to 23.2), confirming the inheritance and genetic basis of phenotypic resistance. In vitro assays of ACCase inhibition by diclofop acid indicated that resistance was due to a non-target-site mechanism. Following selection with diclofop-methyl, the five L. rigidum populations exhibited diverse patterns of crossresistance to ACCase and ALS-inhibiting herbicides, suggesting that different genes or gene combinations were responsible for resistance. The relevance of these results to the management of herbicide resistance are discussed. Heredity (2005) 95, 485-492.

show abstract

Section: Discussionmentioning

confidence: 99%

High survival frequencies at low herbicide use rates in populations of Lolium rigidum result in rapid evolution of herbicide resistance

2005

View full text Add to dashboard Cite

show abstract

“…Barley and wheat ALS enzymes are sensitive to sulfonylurea herbicides in vitro 19, 20. However, in planta , rapid N ‐demethylation, arylhydroxylation of the phenyl ring followed by glycosylation and cleavage of the sulfonylurea bond result in non‐toxic metabolites and provide the basis for this non‐target site based tolerance 21–23. Metabolisation of nearly 100% of chlorsulfuron, another sulfonylurea, occurs in 24 h in wheat, whereas this herbicide remains intact in sensitive plants 19…”

Section: Introductionmentioning

confidence: 99%

Common and distinct gene expression patterns induced by the herbicides 2,4‐dichlorophenoxyacetic acid, cinidon‐ethyl and tribenuron‐methyl in wheat

Pasquer

Ochsner

Zarn

et al. 2006

Pest Management Science

View full text Add to dashboard Cite

In wheat, herbicides are used to control weeds. Little is known about the changes induced in the metabolism of tolerant plants after herbicide treatment. The impact of three herbicides [2,4-dichlorophenoxyacetic acid (2,4-D), cinidon-ethyl and tribenuron-methyl] on the wheat transcriptome was studied using cDNA microarrays. Gene expression of plants grown in a controlled environment or in the field was studied between 24 h and 2 weeks after treatment. Under controlled conditions, 2,4-D induced genes of the phenylpropanoid pathway soon after treatment. Cinidon-ethyl triggered peroxidase and defence-related gene expression under controlled conditions, probably because reactive oxygen species are released by photo-oxidation of protoporphyrin-IX. The same genes were upregulated in the field as under controlled conditions, albeit at a weaker level. These results show that cinidon-ethyl specifically induces genes involved in plant defence. Under controlled conditions, tribenuron-methyl did not change the expression profile immediately after treatment, but defence-related genes were upregulated after 1 week. Sulfonylurea compounds such as tribenuron-methyl specifically inhibit acetolactate synthase and are rapidly detoxified, but the activity of some of the resulting metabolites could explain later changes in gene expression. Finally, overexpression of the isopropylmalate synthase gene, involved in branched-chain amino acid synthesis, and of defence-related genes was observed in the field after sulfonylurea treatment.

show abstract

“…In turn, there is a conjugation of the herbicidal molecule with UDP-glucose through the enzyme glycosyl transferase or with GHS by the enzyme glutathione S-transferases (GSTs) (Anzalone, 2010), which are substrates for conversion into non-phytotoxic peptide conjugates (Owen, 1991). Possibly increased doses of the herbicide have caused greater absorption of metribuzin by carrots, which may have exceeded the plant inherent capacity to metabolize the herbicide.…”

Section: Resultsmentioning

confidence: 99%

Selectivity of Metribuzin in Postemergence of Culture of Carrot

Carneiro

Silva²,

Barbosa

et al. 2017

Planta daninha

View full text Add to dashboard Cite

-The initial slow growth and short stature of carrot can allow that weeds settle in crop areas, requiring the management of these plants for productivity not to decrease. Nevertheless, weeds control has been difficult because there are few herbicides available for weeds control in postemergence of carrots. Two experiments in the field were carried out to evaluate selectivity of metribuzin applied in postemergence of carrots. A experimental randomized block design was utilized with four repetitions. Treatments consisted of metribuzin doses (0, 144, 288, 432, 576, 720, 960 and 1,200 g ha -1 ), applied in postemergence of carrots of the Nantes variety. Roots productivity was evaluated and percentage of commercial roots and no-commercial roots was calculated. Metribuzin has not caused visual symptoms of intoxication in carrots. Doses lower than 432 g ha -1 of metribuzin do not reduce the total productivity of roots, independent of the application period. Any doses of metribuzin changed the percentage of commercial and noncommercial roots. It is concluded that metribuzin is selective for carrots of the Nantes variety in postemergence applications at doses of 432 g ha -1 .

show abstract

Herbicide Metabolism as a Basis for Selectivity

Cited by 24 publications

References 106 publications

High survival frequencies at low herbicide use rates in populations of Lolium rigidum result in rapid evolution of herbicide resistance

High survival frequencies at low herbicide use rates in populations of Lolium rigidum result in rapid evolution of herbicide resistance

Common and distinct gene expression patterns induced by the herbicides 2,4‐dichlorophenoxyacetic acid, cinidon‐ethyl and tribenuron‐methyl in wheat

Selectivity of Metribuzin in Postemergence of Culture of Carrot

Contact Info

Product

Resources

About