Herbal tea-induced hepatic veno-occlusive disease in China: a case description

Sorting out the plants responsible for a contamination with pyrrolizidine alkaloids in spice seeds by means of LC-MS/MS and DNA barcoding: Proof of principle with cumin and anise spice seeds

“…Indeed, the subset of 1,2-unsaturated PA/PANOs with at least one ester bond at a specific location, as illustrated in Fig. 1 , have been shown to be responsible for large incidents of acute and subacute food poisoning, with high morbidity and mortality ( Kakar et al, 2010 , Li et al, 2021 , Zhu et al, 2021 ). Additionally, long-term intake of small amounts of PA/PANOs has been associated with chronic diseases such as liver cirrhosis, cancer or pulmonary arterial hypertension ( Edgar, Colegate, Boppré, & Molyneux, 2011 , Dusemund et al, 2018 ).…”