Acne being one of the dermatologic problems that affect people at different ages has multiple origins. The purpose of this review is to address whether or not pumpkin seed oil functions as an effective therapy for acne and could be used alongside acne patches. In the introduction, different types of acne are explained with some explanation of how such is developed. This is a crucial introduction to a detailed analysis of how Pumpkin seed oil may be useful in managing acne. The review focuses the diverse types of acne, ranging from non-inflammatory comedowns to inflammatory papules and nodules, highlighting the need for targeted and effective treatment strategies. Pumpkin seed oil, consist of essential fatty acids, antioxidants, and anti-inflammatory properties, emerges as a promising candidate for acne treatment. Review explore about acne patches as a novel and targeted delivery system form pumpkin seed oil. Different types of acne patches are discussed, each designed to address specific aspects of acne pathogenesis.