Herbal polysaccharides and cough reflex

Nosálóvá, G; Flešková, Dana; Jurecek, Ludovit; Sadlonova, V.; Ray, Bimalendu

doi:10.1016/j.resp.2013.03.015

Cited by 43 publications

(37 citation statements)

References 24 publications

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“…This result is in keeping with the previous antitussive effects of licorice. Nosalova et al (2013) showed that an oral extract of polysaccharide from G. glabra [50 mg/kg, per os (p.o.)] suppressed coughing in a citric acid model in guinea pigs; application of this extract produced the strongest antitussive effect (81%) compared with other herbs (Nosalova et al, 2013).…”

Section: Respiratory Studiesmentioning

confidence: 99%

“…Nosalova et al (2013) showed that an oral extract of polysaccharide from G. glabra [50 mg/kg, per os (p.o.)] suppressed coughing in a citric acid model in guinea pigs; application of this extract produced the strongest antitussive effect (81%) compared with other herbs (Nosalova et al, 2013). In another study (Saha et al, 2011), an aqueous extraction of polymeric fraction isolated from G. glabra (50 mg/kg, p.o.)…”

Section: Respiratory Studiesmentioning

confidence: 99%

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Pharmacological Effects ofGlycyrrhizaspp. and Its Bioactive Constituents: Update and Review

2015

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The roots and rhizomes of various species of the perennial herb licorice (Glycyrrhiza) are used in traditional medicine for the treatment of several diseases. In experimental and clinical studies, licorice has been shown to have several pharmacological properties including antiinflammatory, antiviral, antimicrobial, antioxidative, antidiabetic, antiasthma, and anticancer activities as well as immunomodulatory, gastroprotective, hepatoprotective, neuroprotective, and cardioprotective effects. In recent years, several of the biochemical, molecular, and cellular mechanisms of licorice and its active components have also been demonstrated in experimental studies. In this review, we summarized the new phytochemical, pharmacological, and toxicological data from recent experimental and clinical studies of licorice and its bioactive constituents after our previous published review.

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Section: Respiratory Studiesmentioning

confidence: 99%

Section: Respiratory Studiesmentioning

confidence: 99%

Pharmacological Effects ofGlycyrrhizaspp. and Its Bioactive Constituents: Update and Review

2015

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“…There was 67% cough suppression with AV which was comparable with codeine (62%). [33] Asthma A clinical study was conducted to assess the effect of syrup prepared from AV (vasa avaleha) with two different types of dose of AV, namely, aqueous extract (swaras) and heated extract (kwath). The parameters of assessment used were subjective relief in symptoms of asthma observed in patients and certain hematological parameters.…”

Section: Bronchodilatormentioning

confidence: 99%

Untitled

Kapgate¹

2017

IJGP

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Natural products are the most important source for discovery of new and effective drug molecules. The emergence of drug-resistant pathogens and the increase in diseases affecting the immune system have greatly intensified the need to investigate new bioactive metabolites for potential pharmaceutical and industrial applications. Ayurvedic classics have a unique wealth of medicinal plants and vast traditional knowledge of herbal medicine for the cure of various diseases. Adhatoda vasica (Nees) (AV) of family Acanthaceae, is a shrub growing throughout the Indian peninsula. The frequent use of AV has resulted in its inclusion in the WHO manual -The Use of Traditional Medicine in Primary Health Care. Thus, extensive research work has been conducted on the AV. The present article is an endeavor to review the ethanopharmacological evidence of therapeutic uses of AV in nutshell.

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“…Polysaccharides are the potential modifiers of biochemical reactions; they possess emollient, enveloping, immunostimulating, immunomodulating, antitussives, anti-inflammatory, antispasmodic action, antiallergic, antioxidant and antimicrobial activity. [1][2][3][4][5][6][7] The plant derivative, the gum's exudates are of great interest among polysaccharides.…”

Section: Introductionmentioning

confidence: 99%

The Phythochemical Research of Armenian Apricot Gums (Gummi armeniacae)

Babken¹,

Suren²,

Naira³

et al. 2018

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Aim:The plant derivative, the gum's exudates are of great interest among polysaccharides. Nowadays, it is of crucial importance to study the structural peculiarities and the conditioned biological activity of the Gummi Armenicae of native origin as an alternative version of the Gummi Arabicae. Materials and methods: As a material for research served the gum procured from Apricot trees (Armenian Vulgaris Lam.), cultivated in different regions of Armenia annually in spring during juice motion period in 2010-2014 years. The quantity of polysaccharides in gum was determined by the method of gravimetric balance after drying. The quantitative ratio of monosac charide in the examined polysaccharide complex was detected by the method of MRI. Results: By the methods of spectral analysis (PMR 1H and NMR 13C) the structure of Apricot gums polysaccharide fraction was detected. From the analysis of PMR 1H and NMR 13C spectra it is obvious that polysaccharide complex fraction is composed from the rest of α-L-arabionopyranose, β -L-arabionopyranose, α-D-galactopyranose, β -D-galactopyranose, α -D-glucopyranose, β -D-glucopyranose. Low molecular compounds in nonpolar fraction of apricot gum were determined by GC-MS method. The results show that in Rt1=22.5, Rt2=26.3, Rt3=31.4. Simple phenols were registered -peaks of catechols` hydroquinones, pyrogallols, amounts of which are respectively 7.58%, 4.27%, 5.69%.

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Herbal polysaccharides and cough reflex

Cited by 43 publications

References 24 publications

Pharmacological Effects ofGlycyrrhizaspp. and Its Bioactive Constituents: Update and Review

Pharmacological Effects ofGlycyrrhizaspp. and Its Bioactive Constituents: Update and Review

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The Phythochemical Research of Armenian Apricot Gums (Gummi armeniacae)

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