Herbal medicines and phytochemicals for obsessive–compulsive disorder

Abstract

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Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseases

“…Several systematic reviews and assessment reports have been conducted on the clinical efficacy and safety of ginseng, 2,372–374 Eleutherococcus , 375 Rhodiola , 376–382 Withania , 383–388 and other adaptogens on several indications such as cognitive function, 33,72 cardiovascular diseases, 389 chronic pulmonary disease, 390 prevention of common cold, 391 and erectile dysfunction 392 . The clinical evidence of the benefits of W. somnifera in male infertility is also promising but very limited to provide sufficiently robust evidence because of the small number of eligible studies and available data 393 .…”

“…275,355,358,360,363,366 The prophylactic use of adaptogens seems to be justified in healthy subjects for preventing aging-related diseases, and to attenuate stress-induced harmful effects. 26,27,95,317,[368][369][370][371] Several systematic reviews and assessment reports have been conducted on the clinical efficacy and safety of ginseng, 2,372-374 Eleutherococcus, 375 Rhodiola, [376][377][378][379][380][381][382] Withania, [383][384][385][386][387][388] and other adaptogens on several indications such as cognitive function, 33,72 cardiovascular diseases, 389 chronic pulmonary disease, 390 prevention of common cold, 391 and erectile dysfunction. 392 The clinical evidence of the benefits of W. somnifera in male infertility is also promising but very limited to provide sufficiently robust evidence because of the small number of eligible studies and available data.…”

WITHDRAWN: The Chronic Administration of Persian Herbal Formulas Psycodigest Induced The Antidepressant-Like Effect in a Chronic Unpredictable Mild Stress (CUMS) Mouse Model

“…Persian herbal remedies have been employed over thousands of years to cure mental disorders (Ayati et al 2020). There are several medicinal plants in traditional Persian medicine (TPM) used to treatment of depression (Shahmansouri et al 2014;Kolouri et al 2016;Bazrafshan et al 2020).…”

The Hidden Potential of Herbal Remedies and Neutraceuticals in Canine and Feline Behavioural Disorders

“…Mechanism of action of CBD is not yet to be understood completely, but it is known that CBD modulates CB-1 receptor function, GABA, dopamine levels and serotonin function. Several human studies have shown its effectiveness on anxiety and psychotic symptoms and it can be considered as a safe molecule (Ayati et al 2020). Although it is used empirically, many veterinarians successfully use cannabis derivatives in many pathologies such as pain management, mood disorders, anxiety, depression, and seizures in dogs and cats (della Rocca and Di Salvo 2020).…”

“…Withania somnifera, also known as Indian Ginseng has been studied for its neuroprotective, adaptogenic, anxiolytic and antidepressant effects. A randomized clinical trial has demonstrated the effectiveness of withania root extract on depression, anxiety and social dysfunction (Ayati et al 2020). Glycowithanolides (WSG), extracted from the root of Withania somnifera has been used as an anxiolytic by Indians.…”