Herbal Drugs for the Management and Treatment of Herpes Simplex Infections

Suttithumsatid, Wiwit; Panichayupakaranant, Pharkphoom

doi:10.1002/9781119818779.ch13

Cited by 1 publication

(1 citation statement)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, studies have shown that low, non-toxic doses of CUR reduce the infectivity of herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) both in vitro and in vivo, notably decreasing the expression of HSV-1 immediate early genes. 100 Similarly, CUR has been found to reduce immediate early gene expression in human cytomegalovirus (HCMV) infections and exhibit varying effects on Epstein-Barr virus (EBV), inhibiting its reactivation in some studies while enhancing lytic reactivation in others. 101,102 Another study also concluded that various CUR derivatives exhibit excellent absorption, distribution, metabolism, excretion, and toxicity profiles.…”

Section: Skin Infectionsmentioning

confidence: 99%

Advancements in Dermatological Applications of Curcumin: Clinical Efficacy and Mechanistic Insights in the Management of Skin Disorders

Mo,

Yuan,

Guan

et al. 2024

CCID

View full text Add to dashboard Cite

Curcumin, derived from Curcuma longa (turmeric), exhibits significant potential in dermatology, addressing conditions like atopic dermatitis, psoriasis, chronic wounds, skin cancer, and infections through its anti-inflammatory, antioxidant, anticancer, and antimicrobial properties. This review synthesizes evidence on curcumin's mechanisms, including modulation of immune responses and promotion of wound healing, showcasing its efficacy in reducing inflammation, cytokine levels, and enhancing skin barrier functions. Studies highlight curcumin's ability to selectively target tumor cells, suggesting a multifaceted approach to cancer therapy with minimal side effects. Despite promising therapeutic benefits, challenges remain in bioavailability, potency, and targeted delivery, underscoring the need for further research to optimize dosages, delivery methods, and assess long-term safety. The integration of curcumin into dermatological practice requires a balanced consideration of evidence-based efficacy and safety. Curcumin's comprehensive utility in dermatology, coupled with the necessity for advanced scientific exploration, emphasizes the importance of combining traditional knowledge with contemporary research to improve patient care in dermatology. This approach could significantly enhance outcomes for individuals with skin-related conditions, marking curcumin as a versatile and promising agent in the field.

show abstract

Section: Skin Infectionsmentioning

confidence: 99%