Herb-drug interactions

Windrum, P; Hull, DR; Morris, T. G.

doi:10.1016/s0140-6736(05)74767-x

Cited by 30 publications

(9 citation statements)

References 4 publications

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“…These estimated prevalences of vitamin/mineral, herbal, and other supplement use are higher than those derived from previous national surveys [2-4], and by extrapolation, so is the prevalence of concomitant use of supplements and drugs. While many herbal medications and dietary supplements are safe for most people to use [5], there is growing evidence that some herbs and other types of non-herbal supplements can cause serious adverse effects [6-9]. Given the large proportion of this group concurrently using clinician-prescribed medications and self-prescribed dietary supplements, there is a great potential for drug-supplement interactions, especially since several surveys have shown that patients generally do not report or under-report use of supplements to their clinicians and pharmacists [10-13].…”

Section: Introductionmentioning

confidence: 99%

Use of dietary supplements by female seniors in a large Northern California health plan

Gordon

Schaffer

2005

BMC Geriatr

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Background: Women aged ≥ 65 years are high utilizers of prescription and over-the-counter medications, and many of these women are also taking dietary supplements. Dietary supplement use by older women is a concern because of possible side effects and drug-supplement interactions. The primary aim of this study was to provide a comprehensive picture of dietary supplement use among older women in a large health plan in Northern California, USA, to raise awareness among health care providers and pharmacists about the need for implementing structural and educational interventions to minimize adverse consequences of self-directed supplement use. A secondary aim was to raise awareness about how the focus on use of herbals and megavitamins that has occurred in most surveys of complementary and alternative therapy use results in a significant underestimate of the proportion of older women who are using all types of dietary supplements for the same purposes.

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Section: Introductionmentioning

confidence: 99%

Use of dietary supplements by female seniors in a large Northern California health plan

Gordon

Schaffer

2005

BMC Geriatr

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“…What is more is, as that integrative medicine therapy with both conventional western medicine and tradition medicine becomes the new trend in current medical care, the combined applications of herbs and drugs are increasing. And the potential of interactions between them causes more and more attention worldwide [51–55]. Herb-drug interaction has hence become an important focus of this systematic review.…”

Section: Discussionmentioning

confidence: 99%

Is Yangxue Qingnao Granule Combined with Antihypertensive Drugs, a New Integrative Medicine Therapy, More Effective Than Antihypertensive Therapy Alone in Treating Essential Hypertension?

Wang

Yang

Feng

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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Background. Yangxue Qingnao granule (YQG) combined with antihypertensive drugs, a new integrative medicine therapy, has been widely used for essential hypertension (EH) in China. This study aims to assess the current clinical evidence of YQG combined with antihypertensive drugs for EH. Methods. Randomized controlled trials(RCTs) published between 1996 and 2012 on YQG combined with antihypertensive drugs versus antihypertensive drugs in treating EH were retrieved from six major electronic databases, including The Cochrane Library, PubMed, Chinese National Knowledge Infrastructure, Chinese Scientific Journal Database, Chinese Biomedical Literature Database, and Wanfang Data. Meta-analysis was performed on the overall effects on blood pressure. Results. Twelve randomized trials were included. Methodological quality of the trials was evaluated as generally low. Meta-analysis showed that YQG combined with antihypertensive drugs demonstrated potential effect for lowing either SBP (MD: −7.31 [−11.75, −2.87]; P = 0.001) or DBP (MD: −5.21 [−8.19, −2.24]; P = 0.0006) compared to antihypertensive drugs alone. Conclusions. It indicated that YQG combined with antihypertensive drugs is more effective than antihypertensive drugs alone in treating EH. However, more RCTs of larger scale, multicentre/country, longer follow-up periods, and higher quality are required to verify the efficacy of integrative medicine therapy over all antihypertensive therapies.

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“…Another interaction of concern involves the polyherbal mixture, which increases blood concentrations of prednisolone. [3233]…”

Section: Aristolochic Acidmentioning

confidence: 99%

A brief study of toxic effects of some medicinal herbs on kidney

Asif¹

2012

Adv Biomed Res

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Increased use of complementary and alternative herbal medicines in the treatment of various diseases.Some herbal therapies may be causes of potential toxicity that may be renal toxicity caused by the ingestion of herbs. The goal of this study is the toxic and beneficial effects of medicinal herbs on renal health by which evidence for benefit or toxicity has been found. Included are nephrotoxicity from aristolochic acid and other components within herbs, herb-drug interactions, heavy metal toxicity in herbs and adulterants during careless preparation of herbal medicine, resulting in adverse renal effects and renal toxicity from contaminants within the extracts. The review aims to provide knowledge and guide to encourage future toxicity studies on the kidney by medicinal herbs.

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Herb-drug interactions

Cited by 30 publications

References 4 publications

Use of dietary supplements by female seniors in a large Northern California health plan

Use of dietary supplements by female seniors in a large Northern California health plan

Is Yangxue Qingnao Granule Combined with Antihypertensive Drugs, a New Integrative Medicine Therapy, More Effective Than Antihypertensive Therapy Alone in Treating Essential Hypertension?

A brief study of toxic effects of some medicinal herbs on kidney

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