“…HER2 expression was also associated with large tumor size(>3cm) (OR=0.40; 95% CI:0.26–0.63; p<0.01) ( 14 , 17 , 20 , 23 , 27 ) ( Figure 2D ). In the HER2 positive tumors, the proportion of Ta stage was significantly lower than that in the negative tumors (OR=2.52;95%CI:1,58–4.01; p<0.01) ( 14 , 21 , 24 , 25 , 27 ) ( Figure 3A ). Furthermore, HER2 expression was linked with high tumor grade (OR=0.23; 95% CI:0.15–0.35; p<0.01) ( 14 – 18 , 20 , 23 – 27 ) ( Figure 3B ) and lymph node metastasis (OR=0.52; 95% CI:0.38–0.71; p<0.01) ( 15 , 16 , 21 , 25 , 26 ) ( Figure 3C ).…”