Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats

Antiosteoporotic compounds from seeds of Cuscuta chinensis

“…Kaempferol and hyperoside are reported to be the major compound in C. australis and C. chinensis, respectively (Ye et al, 2005), and our study indicates there may be no significant difference for these two very close species when used to treat osteoporosis. Compared with other reports concerning the antiosteoporosis by TSZ aqueous extracts, our ethanolic extract is much more potent and this further proves the hypothesis that the bioactive constituents of TSZ are in ethanolic fraction (Yen et al, 2007). These results with those reported (Miyake et al, 2003;Wattel et al, 2003;Prouillet et al, 2004) suggest that kaempferol and hyperoside may represent new pharmacological tools for the treatment of osteoporosis.…”

“…Tu-Si-Zi (TSZ), the dried seeds of Cuscuta chinensis Lam (Family Convolvulaceae), is an important Chinese traditional medicine widely used to improve sexual function, prevent and treat cardiovascular diseases, treat osteoporosis, and prevent senescence (Zheng et al, 1998). Moreover, it possesses antitumoral, hepaprotective and neuropotective effects (Nisa et al, 1986;Liu et al, 2003;Umehara et al, 2004;Yen et al, 2007). The active constituents of TSZ include flavonoids, lignans, quinic acids and polysaccharides (Du et al, 1998;Wang et al, 2000;Ye et al, 2002bYe et al, , 2005He et al, 2010).…”

Anti-hyperlipidemic activity of spider brake (Pteris multifida) with rats fed a high cholesterol diet

“…In previous studies, it was found that many Taiwanese folk herbs have pharmacological functions such as anti-inflammation, anti-virus, anti-cancer, immune enhancement, antioxidant, anti-aggregation and hepatoprotection (Chang et al, 2005;Hsu et al, 2005;Kuo et al, 2004;Lin et al, 2000Lin et al, , 2002Lin et al, , 2007Lu et al, 2000;Wu et al, 2004;Yang et al, 2005Yang et al, , 2007Yen et al, 2007).…”

Chemical composition and hepatoprotective activity of ethanolic root extract of Taraxacum Syriacum Boiss against acetaminophen intoxication in rats

“…Acetaminophen (paracetamol, N-acetyl-p-aminophenol; APAP) is one of the common drugs used for its analgesic and antipyretic effects (1)(2). At therapeutic doses, it is believed APAP is safe and principally metabolized in liver by glucuronidation and sulfation (1,3).…”

“…In spite of the fact that APAP is safe at therapeutic doses, but it induces acute liver failure through the production of centrilobular hepatic necrosis when taken in higher doses (4)(5)(6). Previous studies have shown increases in Reactive oxygen species (ROS) production during APAP toxicity has a central role in APAP-induced damage to hepatocytes (2,4).…”