“…In some HCCs with bile duct invasion, a fragment or fragments of the intracavitary growth may detach and be situated (frequently together with clotted blood) as a floating mass or tumor debris in the lumen (the "tumor thrombus"), and subsequently be dislocated to other places of the biliary tract (e.g., the ampullary region), analogous to an embolus ("tumor embolus"). Dickinson and Santulli (1962), Gerson und Schinella (1969), Brand et al (1976), Kawakami et al (1977), Afroudakis et al (1978), Cleland and Adjukiewicz (1980), Jurco and Kim (1980), Joehl andAbt (1984), Roslyn et al (1984), Oshima et al (1986), Sarma et al (1987), Komatsu et al (1989), Kiev et al (1990), Lau et al (1990), Schutze et al (1990), Lai et al (1992), Kirk et al (1994), Wang et al (1995), Sastry et al (1996), Nakajima et al (1997), Satoh et al (2000), Shiomi et al (2001), Tamada et al (2001),Tanizaki et al (2001), Tseng et al (2001, Nishio et al (2002), Murakami et al (2003), Peng et al (2004), Hanaoka et al (2006), Gabata et al (2007, Kobayashi et al (2008), Long et al (2010, andWang et al (2010).…”