Hepatocyte Growth Factor Production may be Related to the Inflammatory Response in Patients With Acute Myocardial Infarction.

Hepatocyte Growth Factor and Cardiovascular Thrombosis in Patients Admitted to the Intensive Care Unit

“…Other investigators found that there is an increase in serum HGF in patients with AMI and unstable angina. 26,27,29,35,36 Our results are similar to those reports. Soeki et al suggested that the serum HGF concentration peaked at 7 days after the onset of AMI, and it was related to left ventricular remodeling.…”

“…35 Shimada et al reported that the serum HGF concentration on the 7th day of AMI had a relationship with C-reactive protein, and that HGF was involved in the inflammatory reaction. 36 However, in the present study, the serum HGF concentration was measured only on arrival at the hospital, because Matsumori et al found that the serum HGF concentration increased after heparin administration. 37 Several investigators have reported elevations of serum HGF in patients with myocardial ischemia.…”

Elevated Plasma Levels of Oxidized Low-Density Lipoprotein Relate to the Presence of Angiographically Detected Complex and Thrombotic Coronary Artery Lesion Morphology in Patients With Unstable Angina

“…2,3 Oxidized low-density lipoprotein (ox-LDL) is generally considered to be a key factor in the genesis of the inflammatory process in atherosclerotic lesions 4,5 and the detection of ox-LDL in human plasma has opened new avenues of the study of its relationship to the atherosclerotic process. [6][7][8][9][10] We developed a sandwich enzyme-linked immunosorbent assay (ELISA) method to measure plasma ox-LDL levels, using a specific anti-ox-LDL monoclonal antibody (DLH3) and an antiCirculation Journal Vol.71, May 2007 apolipoprotein B (apoB) polyclonal antibody.…”

Office Cardiologists Cooperative Study on Whole Blood Rapid Panel Tests in Patients With Suspicious Acute Myocardial Infarction

“…Its sensitivity was 50% for patients visiting within 3 h of onset, which is the most beneficial time-frame for performing coronary reperfusion therapy to salvage the myocardial infarct and thus improve long-term prognosis. 18,19 The present comparative study clearly demonstrated a markedly higher sensitivity of the rapid H-FABP test (100%) for diagnosing AMI in this early acute phase and its use should therefore assist in the making of earlier and appropriate therapeutic decisions.…”