Hepatocellular adenoma.

A 70-year-old female visited to tertiary care hospital with complains of abdominal pain on and off for 2 years. Pain gradually increased and was associated with vomiting. Patient is a known case of hypertension and diabetes mellitus. The patient`s complete blood count was normal with increased coagulation profile. Provisional clinical diagnosis was fibronodular variant of hepatocellular carcinoma. Computed tomography scan suggestive of fibronodular hyperplasia. Specimen received in pathology department, which on gross examination showed well circumscribed, well encapsulated tumour with variegated appearance. Histopathological diagnosis of Hepatic adenoma was made.

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“…In fact, radiological findings in patient with HA are often similar to those in patients with HCC. [9][10][11]…”

Section: Microscopic Examinationmentioning

confidence: 99%

Hepatic adenoma-an unusual case report

Joshi

Shukla

Jivani³

et al. 2022

Int J Res Med Sci

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“…Method of delivery was unreported in three pregnancies. 30,50 Results from non-pooled data One single center retrospective study reported surgical interventions and outcomes in 122 HCA patients. 3 The report included nine patients with HCA during pregnancy and observed "moderate progression" without reporting actual size.…”

Section: Outcome Of Invasive Interventions During Pregnancymentioning

confidence: 99%

Behavior and complications of hepatocellular adenoma during pregnancy and puerperium: a retrospective study and systematic review

Haring

Spijkerboer

Cuperus

et al. 2021

HPB

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Background: Hepatocellular adenomas (HCA) are benign liver tumors at risk of hemorrhage. The influence of pregnancy on HCA growth and potential bleeding remains unclear. This study investigates HCA-associated behavior and bleeding complications during or shortly after pregnancy. Methods: (I) Single center retrospective cohort study of HCA during and after pregnancy (II) Systematic literature review.Results: The retrospective study included 11 patients, of which 4 with HCA 5 cm. In only two patients HCA showed growth during pregnancy. In this local cohort, no HCA-related hemorrhages occurred during median follow-up of 34 months (interquartile range 19-58 months). The systematic review yielded 33 studies, totaling 90 patients with 99 pregnancies. Of 73 pregnancies without prior HCA-related intervention, 39 HCA remained stable (53.4%), 11 regressed (15.1%), and 23 (31.5%) progressed.Fifteen HCA-related hemorrhages occurred in HCA measuring 6.5-17.0 cm. Eight patients experienced bleeding during pregnancy, two during labor and five postpartum.Discussion: Although hemorrhage of HCA during or shortly after pregnancy is rare and only reported in HCA 6.5 cm, it can be fatal. Pregnancy in women with HCA, regardless of size, warrant a close surveillance strategy. Observational studies on behavior and management of HCA 5 cm during and immediately after pregnancy are needed.

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“…7). HA commonly shows the common radiological findings of benign hepatocellular lesions with intra‐ and interlesion variety [8, 32]. Intratumoral hemorrhage is frequently identified, especially in larger lesions (Fig.…”

Section: Specific Radiological Findings In Each Diseasementioning

confidence: 99%

“…Intratumoral hemorrhage is frequently identified, especially in larger lesions (Fig. 7) [32]. Only a few reports have described SPIO‐enhanced MR findings of HA, but recent reports describe that HA usually shows slight uptake of SPIO, albeit lower than that of other benign lesions (Fig.…”

Section: Specific Radiological Findings In Each Diseasementioning

confidence: 99%

A pictorial review of benign hepatocellular nodular lesions: comprehensive radiological assessment incorporating the concept of anomalous portal tract syndrome

Ueda

Starkey

Mori

et al. 2010

J Hepato Biliary Pancreat

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Background/purpose Although the pathological categorization system advocated by the International Working Party (IWP) on Terminology has been helpful in categorizing benign hepatocellular lesions, the diverse clinicopathological features of the lesions still cause confusion of diagnosis in clinical settings. Recently, an integrated disease concept termed ''anomalous portal tract syndrome'' (APTS) has been proposed as a congenital anomaly of the portal tract, being a single unifying etiological factor underlying the disorder. In this article, we discuss the radiological features of benign nodular hepatocellular lesions incorporated in the concept of APTS. Methods We systematically reviewed the literature on benign hepatocellular lesions based on the concept of APTS, as well as standard IWP terminology. For this pictorial review, we selected six representative cases and assessed the radiological features of the cases based on the concept of APTS. Results The comprehensive assessment based on APTS enabled the systematic categorization of benign hepatocellular lesions, including nodular regenerative hyperplasia, large regenerative nodules, partial nodular transformation, focal nodular hyperplasia, and hepatocellular adenoma, and was helpful in understanding the overlapping features of these lesions. Conclusions Although the disease concept of APTS is still evolving, it is nonetheless helpful in comprehensively understanding the clinicopathological and radiological features of various benign hepatocellular lesions.

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Hepatocellular adenoma.

Cited by 6 publications

References 3 publications

Hepatic adenoma-an unusual case report

Hepatic adenoma-an unusual case report

Behavior and complications of hepatocellular adenoma during pregnancy and puerperium: a retrospective study and systematic review

A pictorial review of benign hepatocellular nodular lesions: comprehensive radiological assessment incorporating the concept of anomalous portal tract syndrome

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