Hepatocarcinoma in Association with the Alagille Syndrome

Management of Large Hepatocellular Carcinoma in Adult Patients with Alagille Syndrome: A Case Report and Review of Literature

“…Since the syndrome was first described in 1987, less than 20 cases of HCC have been reported in the world literature and only seven cases in adults [10][11][12][13][14][15][16][17][18]. Table 1 summarizes all reported cases of HCC in the English language.…”

Hepatocellular Carcinoma in Children with Alagille Syndrome

“…HCC has been reported as a complication of Alagille syndrome in 6 children (4‐8) and 10 adults (3,6,11‐18). The reported pediatric cases are in two distinct age groups: four in early childhood (age 2‐4) (4‐6,8) and two in adolescence (age 16‐17) (6,7).…”

Arteriohepatic dysplasia (Alagille's syndrome): unusual hepatic architecture and function

“…Previous reports of the various skeletal abnormalities of patients with this syndrome were summarized by Rosen field et al in 1980 and by Brunelle et al in 1986 [3, 12]. Of interest are three separate case reports of hepatocellular carcinoma in association with Alagille's syndrome [13][14][15]. In all three cases, CT scan of the liver was performed; two had MRI scans, two had sonograms, and one had a Tc99m DISIDA scan.…”