Hepatoblastoma in Fine Needle Aspirates

Cytologic Diagnosis of Small Cell Anaplastic Hepatoblastoma

“…The recent cytologic literature contains studies and case reports on the reliability of FNA in the diagnosis and subtyping of pediatric hepatic neoplasms. [5][6][7][8][9][10][11] Accumulation and sharing of the knowledge of the typical cytologic features will help achieve a more accurate cytologic diagnosis. 6 The anaplastic small cell subtype of HB has the worst prognosis.…”

“…[2][3][4] This subtype is also the least common, with the majority of reported cases the epithelial or mixed subtype. [5][6][7][8][9][10][11] The cytopathologic findings helpful in subtyping HB have been described earlier. 10,11 The anaplastic subtype shows a very immature cytologic appearance.…”

“…2 The last type is the least common and has the poorest prognosis. [2][3][4] Despite the increasing use of fine needle aspiration (FNA) for the preoperative evaluation of HB, [5][6][7][8][9][10][11] there are relatively few articles describing the cytologic characteristics of this uncommon subtype. 4,10 In this report we describe the cytologic features of a case of undifferentiated small cell HB and discuss the differential diagnosis versus other pediatric hepatic neoplasms.…”

Fine Needle Aspiration Cytology of Hepatoblastoma

“…Discussion HBL is a rare tumor, and as such the number of published cases documenting the cytologic features on FNAC [23][24][25] are few when compared to much larger histologic series. [2][3][4][5][6][7][8][9][10][11][12][13] To the best of our knowledge, the present series was the largest reported to date, and our findings largely concur with those of earlier reports.…”

“…14,21 The diagnosis of mixed HBL on FNAC was reported earlier. 22 Us-Krasovec et al 25 could correctly identify 4 of 6 mixed HBLs on FNAC. This was not our experience in this larger series.…”