Hepatoblastoma in a neonate: a hypervascular presentation mimicking hemangioendothelioma

Ingram, James D.; Yerushalmi, Baruch; Connell, John R.; Karrer, F. M.; Tyson, R. Weslie; Sokol, Ronald J.

doi:10.1007/s002470000320

Cited by 33 publications

(46 citation statements)

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“…[4] In our case ultrasound abdomen showed a large heterogeneous mass with specks of hyperechogenecity. CECT abdomen revealed large peripherally enhancing mass arising from left lobe of liver with hyperdense areas suggesting calcific foci [ Figure 1].…”

Section: Discussionsupporting

confidence: 45%

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Infantile Hemangioendothelioma of Liver: Case Report

Krishna¹,

Geetha²,

Malleboyina³

et al. 2015

jemds

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Infantile Hemangioendothelioma of the liver is an uncommon tumor. Two subtypes have been described. Type1 has recognizable but irregularly dilated vascular spaces in a fibromyxomatous stroma. Type 2 is described as having a more aggressive histology. It is marked by poorly formed and anatomising channels with papillae lined by atypical endothelial cells and is potentially malignant. Clinical presentation is variable, hepatomegaly or abdominal mass, some hematological abnormalities may be seen. In laboratory investigation, or lesion may be asymptomatic and discovered incidentally. We report a case of 45 day old female child who presented with abdominal distension. CT abdomen showed hypoattenuating mass in the left lobe of the liver along with specks of calcification.. The mass was excised and had large areas of gritty calcification simulating a teratoma. however histopathological diagnosis of infantile hemangioendothelioma type I of liver was made. Hemangioendothelioma of the liver has been reported as most common benign symptomatic vascular tumor of the liver in infancy.

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Section: Discussionsupporting

confidence: 45%

“…Surgical resection is indicated if life threatening symptoms are present or if the mass cannot be distinguished from a malignant tumor radiologically. [4] …”

Section: Discussionmentioning

confidence: 99%

Infantile Hemangioendothelioma of Liver: Case Report

Krishna¹,

Geetha²,

Malleboyina³

et al. 2015

jemds

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“…The closest differential diagnoses of IHH are hepatoblastoma, metastatic neuroblastoma and mesenchymal hamartoma [6]. In hepatoblastoma, the alphafetoprotein (AFP) levels are persistently, markedly elevated and in metastatic neuroblastoma, urinary levels of catecholamines are elevated along with an adrenal mass [8]. Hamartoma is usually a congenital malformation which appears to be cystic or multicystic.…”

Section: Discussionmentioning

confidence: 99%

Infantile hepatic hemangioma: a diagnostic delimma

Najmuddin¹,

Sharif²,

Kotrashetty³

et al. 2014

RusOMJ

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Abstract:Infantile hepatic hemangioma is a tumor arising from the mesenchymal liver tissue. Presentation varies from being asymptomatic to having life threatening complications. They can manifest as solitary or multicentric lesions. We hereby, report a one and half month old child who presented with respiratory distress and was incidentally found to have a liver mass, which eventually was diagnosed as infantile hepatic hemangioma and successfully treated with propranolol.

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“…Besides the liver, it can be seen in tissues such as the lung, spleen, brain, ovaries, heart, central nervous system, and bone (1-4). Of the cases, 85% are children younger than 6 months and 40%-50% have hemangiomas in their skin (5)(6)(7)(8). It is reported to be seen more commonly in girls than in boys at a rate of 2/1-3/1 (4,6).…”

Section: Introductionmentioning

confidence: 99%

“…Of the cases, 85% are children younger than 6 months and 40%-50% have hemangiomas in their skin (5)(6)(7)(8). It is reported to be seen more commonly in girls than in boys at a rate of 2/1-3/1 (4,6). Hepatic involvement of hemangioendothelioma may be in the nodular or diffuse type, and histopathologic calcification may be seen in 50% of cases.…”

Section: Introductionmentioning

confidence: 99%

A Rare Cause of Hepatomegaly: Infantile Hepatic Hemangiomendothelioma

Gümüştekin¹,

Urgancı²,

Vural³

2016

JAREM

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Infantile hepatic hemangiomendothelioma, a bening vascular neoplasia derived from endothelial cells, is the most common newborn tumor located in the liver. The tumor has female predominancy. Mostly, it is associated with a good prognosis and may show spontaneous regression by the time the infant is 1 year of age. Although most of the patients are asymptomatic, abdominal mass, hepatomegaly, jaundice, nausea, and vomiting can be encountered among common clinical findings. Herein, a 1.5-month-old boy with abdominal distention was referred to our gastroenterology unit for hepatomegaly. Non-invasive diagnostic modalities revealed infantile hepatic hemangioendothelioma.

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Hepatoblastoma in a neonate: a hypervascular presentation mimicking hemangioendothelioma

Cited by 33 publications

References 0 publications

Infantile Hemangioendothelioma of Liver: Case Report

Infantile Hemangioendothelioma of Liver: Case Report

Infantile hepatic hemangioma: a diagnostic delimma

A Rare Cause of Hepatomegaly: Infantile Hepatic Hemangiomendothelioma

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