Hepato-renal toxicities associated with heavy metal contamination of water sources among residents of an oil contaminated area in Nigeria

Thomas, Caroline Chinenyenwa; Nsonwu-Anyanwu, Augusta Chinyere; Usoro, Chinyere Adanna Opara; Agoro, Eni-yimini Solomon; Idenyi, Augusta N.

doi:10.1016/j.ecoenv.2021.111988

Cited by 15 publications

(12 citation statements)

References 17 publications

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“…121,122 In Nigeria, exposure to heavy metals via consumption of contaminated water and food has been associated with increased risk of CKD. 111,123 Studies have also linked exposure to mycotoxin Ochratoxin A contaminated food to CKD. 68 In Tunisia, a case-control study revealed the highest levels of Ochratoxin A in the blood and foods of patients with CKDu and emphasised the causative role of Ochratoxin A in disease onset.…”

Section: Ckd and Environmental Stressorsmentioning

confidence: 99%

Chronic kidney disease of unknown aetiology in Africa: A review of the literature

Fiseha,

Ekong,

Osborne

2023

Nephrology

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During the last two decades, an epidemic of a severe form of chronic kidney disease (CKD) unrelated to traditional risk factors (diabetes and hypertension) has been recognized in low‐ to middle‐income countries. CKD of unknown aetiology (CKDu) mainly affects young working‐age adults, and has become as an important and devastating public health issue. CKDu is a multifactorial disease with associated genetic and environmental risk factors. This review summarizes the current epidemiological evidence on the burden of CKDu and its probable environmental risk factors contributing to CKD in Africa. PubMed/Medline and the African Journals Online databases were searched to identify relevant population‐based studies published in the last two decades. In the general population, the burden of CKD attributable to CKDu varied from 19.4% to 79%. Epidemiologic studies have established that environmental factors, including genetics, infectious agents, rural residence, low socioeconomic status, malnutrition, agricultural practise and exposure to agrochemicals, heavy metals, use of traditional herbs, and contaminated water sources or food contribute to the burden of CKD in the region. There is a great need for epidemiological studies exploring the true burden of CKDu and unique geographical distribution, and the role of environmental factors in the development of CKD/CKDu.image

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Section: Ckd and Environmental Stressorsmentioning

confidence: 99%

Chronic kidney disease of unknown aetiology in Africa: A review of the literature

Fiseha,

Ekong,

Osborne

2023

Nephrology

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“…The oil exploration and exploitation activities, oil spillage, and gas flaring above all have decimated the environment with oil and oil-related waste materials (Kuch and Bavumiragira, 2019;Singh et al, 2020). The devastating state of the communities investigated is evident in the damaged roof-tops, poor water and air quality, lack of soil nutrients, and extinction of some living organisms (Kennish, 2002;Anejionu et al, 2015;Bodo and Gimah, 2020;Ebong et al, 2022. Studies have shown that, crude oil and crude oil-impacted environment has elevated level of trace metals and could be transported into the human system (Chinedu and Chukwuemeka, 2018;Ahiamadu et al, 202l;Thomas et al, 2021). Gupta et al (2014) and Chonokhuu et al (2019) revealed that, a perfect understanding of the pollution status and health risks in an area, a multivariate analysis and speciation studies should be utilized.…”

Section: Introductionmentioning

confidence: 99%

Impact of Seasonal Variations and Oil Activities on the Total Concentrations, Geochemical Fractions, And Human Health Problems of Trace Metals in Soils Within the Oil-Bearing Communities of South-South Region of Nigeria

Ebong¹,

Moses²,

Akpabio³

et al. 2022

BJES

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The impacts of oil activities and seasonal variations on the total concentrations, geochemical fractions, and human health problems of trace metals in soils within oil-bearing communities of Akwa Ibom State, Nigeria were examined. Top soils were obtained from Eket, Onna, Esit Eket, and Ibeno local government areas between January and December, 2017. Samples were also collected from Etinan local government area of the State and used as the Control. The samples and Control were subjected to standard analytical procedures and analysed for their physicochemical properties and total metal concentrations. The modified BCR methods were employed for the speciation of metals. The findings revealed that the pH levels were higher during the dry season while, the electrical conductivity, organic matter, and cation exchange capacity of the studied soils were higher in the rainy season. The total mean concentrations of Pb, As, Cd, Cr, Fe, and V were higher in the dry season whereas, Ni was higher in the wet season. Though, their concentrations were within the acceptable limits. Generally, the concentrations of all the parameters in the studied soils were higher than at the control site. Pb, As, Ni, and V existed predominantly in the reducible fraction, Cd and Cr in acid extractable while, Fe existed mostly in the residual fraction in the studied soils. However, at the control site all the metals except Cd existed mainly in the residual fraction. The study showed that all the studied locations were highly contaminated with these metals and substantial seasonal variations were also recorded for the pollution indices. It was also noted that, seasonal changes and oil activities were the key factors affecting the quality of the studied soils. Daily intake rates for the metals through exposure to soil for both the young and old populations were within their required oral reference doses. The non-carcinogenic risks recorded for both populations were less than one. However, both populations were exposed to high Pb and the younger ones were more susceptible. The study revealed the influence of seasonal change and oil activities on the mobility and toxicity of metals in the studied soils.

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“…Naturally, Nigerian crude oil is known for having high level of toxic metals (Ahiamadu et al, 2021). Consequently, the soil that bears crude oil in Nigeria is expected to also contain elevated levels of these metals (Chinedu and Chukwuemeka, 2018;Thomas et al, 2021). Reports have shown that, oil-bearing soils and oil-related activities have considerable effect on total metals accumulation and speciation in the host soil environment (Borah and Deka, 2023;Duru et al, 2009;Ebong et al, 2022;Ogbo and Okhuoya (2011).…”

Section: Introductionmentioning

confidence: 99%

“…Ana et al (2009) also opined that, the industrial activities within the Niger Delta Region have adverse effects on the health of the inhabitants. Crude oil bearing soil and associated activities have the potentials of increasing the levels of toxic substances in the environment (Ahiamadu et al, 202l;Thomas et al, 2021). Consequently, human beings in the oil producing Region of Nigeria are constantly exposed to high levels of toxic metals and their related human health implications either directly or indirectly (Amadi et al, 2021;Ordinioha and Brisibe, 2013).…”

Section: Introductionmentioning

confidence: 99%

Physicochemical Properties, Total Concentration, Geochemical Fractions, and Health Risks of Trace Metals in Oil-Bearing Soils of Akwa Ibom State, Nigeria

Ebong¹,

Moses²,

Akpabio³

et al. 2022

JMESR

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The physicochemical properties, total metal, metal fractions, and related human health problems of metals in oil-bearing soils of Akwa Ibom State were appraised using standard procedures. The study aimed at assessing the effects of crude oil and related activities on the properties of soil including metals (Cd, Cr, Ni, Pb and V), their fractions and associated health problems. Results showed that, levels of parameters were higher in the soils examined than in the control. The entire metals examined, apart from Cd, were within their acceptable limits however; higher than the limits for agricultural soils. Cd and Cr existed mainly in the readily available fraction, while Ni, Pb, and V occurred mainly in the reducible fraction in the studied soils. Conversely, these metals, except Cd, occurred principally in the inert fraction in the control. V/Ni ratio confirmed the soils as oil-forming continents and of organic matter origin. The natural factor, crude oil, and oil-related activities were major sources of soil contaminants. Anthropogenic proportions of metals were more in the soils investigated than in the background soil. The locations were contaminated with metals. Daily intake rates of metals were within their recommended doses except for Pb. The pollution status of the oil-bearing soils and the related human health risks have been revealed.

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Hepato-renal toxicities associated with heavy metal contamination of water sources among residents of an oil contaminated area in Nigeria

Cited by 15 publications

References 17 publications

Chronic kidney disease of unknown aetiology in Africa: A review of the literature

Chronic kidney disease of unknown aetiology in Africa: A review of the literature

Impact of Seasonal Variations and Oil Activities on the Total Concentrations, Geochemical Fractions, And Human Health Problems of Trace Metals in Soils Within the Oil-Bearing Communities of South-South Region of Nigeria

Physicochemical Properties, Total Concentration, Geochemical Fractions, and Health Risks of Trace Metals in Oil-Bearing Soils of Akwa Ibom State, Nigeria

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