“…There have been reports of cases with involvement of other organs in the HEV infection, such as: acute pancreatitis [35,36], immune-mediated diseases [37][38][39][40], (Hashimoto's thyroiditis, glomerulonephritis, Henoch-Schonlein purpura, myasthenia gravis), hematologic diseases [38,41], (hemolytic anemia, acute myeloid leukemia, severe, thrombocytopenia), mixed cryoglobulinemia [42], infl ammatory bowel disease [43]. In pregnant women, infected during the fi rst trimester it generates a 15% to 25% lethality, in the Eastern hemisphere [44,45].…”