Hepatitis C Virus Recurrence After Liver Transplantation: Influence of Immunosuppressive Regimens on Viral Load and Liver Histology

Cyclosporine and psoriasis: 2008 National Psoriasis Foundation Consensus Conference

“…107 Recent research has shown that cyclosporine suppresses HCV replication in vitro and may, therefore, not exacerbate HCV infection when given as a treatment for psoriasis in patients with concomitant disease. 108 One such case report showed an improvement in PASI score from 29 to 7, with no elevation in liver function tests, HCV RNA, or core protein after 56 weeks of cyclosporine therapy. 109 Similar studies found that cyclosporine treatment in patients with HCV infection is not harmful to liver histology.…”

Prevalence of hepatitis B and C and risk factors for nonvaccination in inflammatory bowel disease patients in Northeast France

“…En 2006, une étude multicentrique, prospective de 66 patients greffés hépatiques pour VHC en récidive, comparait l'influence du traitement immunosuppresseur sur la charge virale et le score histologique de fibrose. Ces deux paramètres n'étaient pas significativement modifiés par la ciclosporine [58]. En rhumatologie, certains auteurs préconisent l'utilisation de la ciclosporine chez les patients porteurs de maladies auto-immunes et d'hépatite C dans le sens où celle-ci semble efficace et sans risque de réactivation [59].…”

Pattern of Recurrent Hepatitis C in Deceased vs Living Donor Liver Transplantation: An Egyptian Experience

“…Cyclosporine had antiviral properties in vitro DQG ZDV DVVRFLDWHG ZLWK D VLJQL¿FDQWO\ lower risk of recurrence of HCV 24 and less fibrosis. 25 However, no compelling data suggested that there was an advantage to using either tacrolimus or cyclosporine in clinical practice. 26,27 In DDLT group, pulse steroid therapy ZDV VLJQL¿FDQWO\ UHODWHG WR +&9 UHFXUUHQFH S This might be due to the increased use of pulse steroid to treat rejection which was encountered more in this group (possibly due to prolonged ischemia time).…”