Hepatitis C Virus Infection in Children

Squires, James E.; Balistreri, William F.

doi:10.1017/9781108918978.019

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2022

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“…In children, acute hepatitis C virus (HCV) infection is rare, 0.05 to 0.36% in the United States; however, it may be underestimated. 1 Seven different genotypes of HCV have been reported; however, in Iran, genotype I and III are the most common ones, respectively. Similarly, the usage of injections/syringes in health care facilities is one of greatest risks of the infection in Iran.…”

Section: Introductionmentioning

confidence: 99%

Acute Hepatitis C Virus Infection Treated with Daclatasvir/Sofosbuvir in a 9-Year-Old Boy

Rahmani

Farahmand

Heidari

2022

Journal of Child Science

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The present study includes a case report of a 9-year-old boy who came to our center with jaundice, elevated liver enzymes, and palpable liver. He was treated with ursodeoxycholic acid, but no improvement in symptoms was seen. Reverse transcription polymerase chain reaction and liver biopsy were positive for hepatitis C virus. He was treated with daclatasvir/sofosbuvir for 3 months. Daclatasvir/sofosbuvir might be effective against the treatment of hepatitis in children, with no report of remission and minimal side effects.

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Section: Introductionmentioning

confidence: 99%