Hepatitis C in Hospital Employees with Needlestick Injuries

Kiyosawa, Kendo; Sodeyama, Takeshi; Tanaka, Eiji; Nakano, Yoshitaka; Furuta, Seiichi; Nishioka, Kusuya; Purcell, Robert H.; Alter, Harvey J.

doi:10.7326/0003-4819-115-5-367

Cited by 318 publications

(107 citation statements)

References 9 publications

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“…[54][55][56] Transmission has also been associated with organ transplantation, hemodialysis, tattooing, and sharing contaminated equipment in parts of the world where the HCV prevalence is high.…”

Section: 53mentioning

confidence: 99%

Hepatitis C: a review for primary care physicians

Wong

Lee²

2006

Canadian Medical Association Journal

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Primary care physicians see many of the estimated 250 000 Canadians chronically infected with the hepatitis C virus (HCV). Of this number, about one-third are unaware they are infected, which constitutes a large hidden epidemic. They continue to spread HCV unknowingly and cannot benefit from advances in antiviral therapy that may clear them of the virus. Many HCV-infected people remain asymptomatic, which means it is important to assess for risk factors and test patients accordingly. The third-generation enzyme immunoassay for HCV antibodies is a sensitive and specific test, although the presence of the virus can be confirmed by polymerase chain reaction testing for HCV RNA in some circumstances. Pegylated interferon-α and ribavirin combination therapy clears the virus in about 45%-80% of patients, depending on viral genotype. Preventive strategies and counselling recommendations are also reviewed. CMAJ 2006;174(5):649-59 Abstract

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Section: 53mentioning

confidence: 99%

Hepatitis C: a review for primary care physicians

Wong

Lee²

2006

Canadian Medical Association Journal

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“…The seroconversion rate for Hepatitis C Virus (HCV) in a Japanese hospital, for example, was previously shown to be 3% 8) , while a study from Turkey 9) revealed that approximately 8% of nurses surveyed were already carrying this disease.…”

mentioning

confidence: 99%

Hospital Safety Climate, Psychosocial Risk Factors and Needlestick Injuries in Japan

et al. 2010

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“…HcV may be transmitted by exposure to blood, semen and cerebral spinal fluid (3)(4)(5). Percutaneous HcV transmission may occur following needle-stick injures or cuts from other sharp instruments.…”

Section: Introductionmentioning

confidence: 99%