Hepatitis B virus carrier rate, prevalence and susceptibility and impact of immunization program among households in the city of Taiz, Yemen

Sallam, Talal A.; Bahaj, Saleh Salem; Al-Shami, Abdulkareem Mohammed; Lu, Mengji; Roggendorf, Michael; Tong, C. Y. William

doi:10.1016/j.vaccine.2012.06.008

Cited by 11 publications

(8 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Blood donors came from different regions of the governorates this reflected to some extent the prevalence of HBV in this community but more precisely reflecting the prevalence among healthy adult blood donors. The present study indicated that 2.6% of blood donors were positive HBsAG and this figure was higher compared to a study conducted in Yemen and among blood donors that showed a prevalence of 2.1% (14) and lower compared to a Study conducted in Yemen (4.2 %) (15). These differences in the prevalence rates might be explained by the geographical differences in the availability of services and vaccination of programs.…”

Section: Discussioncontrasting

confidence: 80%

Prevalence of Hepatitis B Virus Infection and Associated Factors Among Blood Donors in 48 Hospital Sana'a City- Yemen During 2016

Alnwany¹

2020

Journal of Medical and Pharmaceutical Sciences

View full text Add to dashboard Cite

Aim: This study was conducted to determine the prevalence of hepatitis B virus (HBV) and associated factors. Method: A cross-sectional study was conducted on randomly (simple random sample according to previous seroprevalence HBV in population) selected 500 blood donors from who came to the blood bank service in 48 Hospital in Sana'a between October 2016 to Aug 2016 and were interviewed face to face, then data was collected by using questionnaire and blood samples collected after that using enzyme-linked immunosorbent assay technique. the questionnaire consisted of three sections (A) demographics, (B) associated factors and (C) blood sample results. Results and conclusion: The prevalence of hepatitis B virus infected was 2.6%. Only three factors in simple and multiple logistic regression were statistically significant with prevalence of HBsAG. Multiple logistic regression analysis showed that blood donors who had history of: dental treatment, cupping and malaria infection were more likely to infect with hepatitis B virus infected compared to those without history of: dental treatment, cupping and malaria infection 7.8%, 7.3 % and 7.5 % respectively. The rest of factors failed to achieve any statistical significant with prevalence of HBsAG. Hepatitis b is hyper endemic in Yemen, this need application of infection control policies in dental clinics, cupping centers, inject Hepatitis B virus vaccine and control of malaria in endemic areas.

show abstract

Section: Discussioncontrasting

confidence: 80%

Prevalence of Hepatitis B Virus Infection and Associated Factors Among Blood Donors in 48 Hospital Sana'a City- Yemen During 2016

Alnwany¹

2020

Journal of Medical and Pharmaceutical Sciences

View full text Add to dashboard Cite

show abstract

“…The HBeAg negativity among the donors supports this. We have previously reported subjects with no HBV markers in two independent reports of blood donors [25] and in the general population [26] in Yemen, and as a result, we proposed immunizing adults as an adjunct to the ongoing expanded infant immunization program, a recommendation that seems valid for the situation revealed by the current study. One more possibility is that the cohort of donors between 16 and 21 years of age with no HBV markers and who were born during HBV vaccination had lost their anti-HBs over the years following vaccination.…”

Section: Discussionmentioning

confidence: 71%

Prevalence of serological markers and nucleic acid for blood-borne viral infections in blood donors in Al-Baha, Saudi Arabia

Almutairi

AlAhmari²,

Al-Zahran³

et al. 2016

J Infect Dev Ctries

View full text Add to dashboard Cite

Introduction: Data on blood-borne viral infections in some regions in Saudi Arabia remain scarce. This study investigates the prevalence of serological markers and nucleic acid for blood-borne viruses among blood donors in Al-Baha, Kingdom of Saudi Arabia. Methodology: In this cross-sectional study, 2,807 donors who donated blood between January 2009 and November 2011 were investigated for blood-borne viral serological markers including HBsAg, anti-HBc, anti-HBs, anti-HCV, anti-HIV, and anti-HTLVI/III in addition to viral nucleic acid. Results: All donors were males between 16 to 66 years of age (mean: 31.5 ± 9.3 years). Viral nucleic acid and/or serological markers were detected in a total of 36 (1.3%) donors; of them, 26 (72.2%) had nucleic acid concomitant with serological markers, 6 (16.7%) had only viral nucleic acid, while 4 (11.1%) had only serological markers. Of all donors, 22 (0.8%) had HBsAg, 227 (8.0%) had anti-HBc, 157 (5.0%) had anti-HBs, 2,577 (91.8%) had no HBV markers, 2 (0.07%) had anti-HIV, 1 (0.04%) had anti-HCV, and 1 (0.04%) had anti-HTLVI/II. The donors who were born during HBV vaccination era showed no HBsAg (0.0%; p = 0.052), lower rates of anti-HBc (1.5%; p < 0.001) and antiHBs (0.7%; p < 0.001), while the majority had no HBV markers (98.5%; p < 0.001). Conclusions: Combined viral nucleic acid and serological testing of donated blood enhances blood safety. The absence of HBV markers among donors suggests susceptibility or declined anti-HBs levels. Thus, HBV revaccination or a vaccine boost among adolescents and adults might be indispensable.

show abstract

“…HBV vaccination coverage rocketed to 70%. HCV antibodies showed a steady decline, while delta antibodies were reported in a very small percentage of HBsAg reactive sera (Al-Shamahy et al, 2003, 2010Sallam et al, 2003Sallam et al, , 2012Al Waleedi and Khader, 2012;Scott et al, 1990).…”

Section: Introductionmentioning

confidence: 97%

Sero-Molecular Epidemiology and Risk Factors of Viral Hepatitis in Urban Yemen

Nabehi¹,

Shamahy²,

Saeed³

et al. 2015

International J. of Virology

View full text Add to dashboard Cite

Viral hepatitis is an acute or chronic neglected disease that affects predominantly the liver. This study aimed to determine the sero prevalence and risk factors for viral hepatitis and HCV genotypes in urban areas of Yemen. In a prospective, cross-sectional, analytical and community-based study and following informed consent, 501 volunteers were randomly recruited. Demographic and clinical data was collected. Screening for HBV, HDV and HCV was carried out using ELISA. HBV/HCV viral loads and HCV genotyping were carried out using COBAS ®

show abstract

Hepatitis B virus carrier rate, prevalence and susceptibility and impact of immunization program among households in the city of Taiz, Yemen

Cited by 11 publications

References 27 publications

Prevalence of Hepatitis B Virus Infection and Associated Factors Among Blood Donors in 48 Hospital Sana'a City- Yemen During 2016

Prevalence of Hepatitis B Virus Infection and Associated Factors Among Blood Donors in 48 Hospital Sana'a City- Yemen During 2016

Prevalence of serological markers and nucleic acid for blood-borne viral infections in blood donors in Al-Baha, Saudi Arabia

Sero-Molecular Epidemiology and Risk Factors of Viral Hepatitis in Urban Yemen

Contact Info

Product

Resources

About