Hepatitis B and C virus prevalence in couples attending an in vitro fertilization clinic in a tertiary care hospital in Saudi Arabia: comparison with ten years earlier

Albadran, Asma; Hibshi, Ali; Saeed, Bahjat A.; Coşkun, Serdar; Awartani, Khalid

doi:10.5144/0256-4947.2017.272

Cited by 6 publications

(4 citation statements)

References 25 publications

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“…Some studies that similarly screened for Hep B (within moderate and high prevalence regions) among pregnant women and their partners, couples who planned to conceive after marriage, and couples who attend a fertility clinic in a tertiary hospital also showed a higher prevalence in men than women (4.6% against 6.8%; 4.4% against 6.3%; and 3.1% against 6.3%, respectively) [32, 46, 47]. By screening and treating couples infected with Hep B, we can more effectively reduce both vertical and horizontal transmission.…”

Section: Discussionmentioning

confidence: 99%

Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study

Talla

Itanyi

Tsuyuki

et al. 2020

Tropical Med Int Health

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Objectives To determine the population prevalence and determinants of hepatitis B (Hep B) status, and status discordance, among pregnant women and their male partners in Nigeria. Methods Cross‐sectional study assessing the seroprevalence of Hep B virus in a cohort of 16 920 pregnant women and their male partners in northcentral Nigeria. Rapid HBsAg antibody test was used for Hep B diagnosis. Demographic, socio‐economic and behavioural information was collected through interviewer‐administered questionnaires and evaluated as determinants of Hep B status and couple status discordance using logistic regression. Results Of 16 920 participants who had a Hep B test result, 6750 couples and 1316 discordant couples were identified. The prevalence of Hep B among all participants was 10.9%, with lower prevalence among pregnant women (10.2%) than their male partners (11.9%), P < 0.001. The prevalence of Hep B sero‐discordance among couples was 19.5% (1316/6750). Younger age, prior Hep B testing and a prior positive Hep B test increased the odds of Hep B infection while being a woman decreased the odds of Hep B among all participants, and among couples. Furthermore, polygamy (adjusted odds ratio [AOR]: 1.49, 95% confidence interval [CI]: 1.19–1.87), prior Hep B testing (AOR: 2.38, 95% CI: 1.14–4.97) and a prior positive Hep B test result were significant determinants of status discordance among the participating couples. Conclusion The prevalence of Hep B among pregnant women and their male partners in northcentral Nigeria is high. A large‐scale intervention is required to reduce Hep B prevalence in this setting.

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Section: Discussionmentioning

confidence: 99%

Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study

Talla

Itanyi

Tsuyuki

et al. 2020

Tropical Med Int Health

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“…HCV seropositivity was equal in females and males. It has been observed in many studies thatHBV infection affects males more than females 12,13,16,25 . There is no clear explanation for this gender variation.…”

Section: Discussionmentioning

confidence: 99%

“…The difference is probably related to the conservative society with less female exposure outside the family, but may also be due to opposite effects of sex hormones. In several experimental animal models, viral transcription is stimulated by androgen, while estrogen suppresses HBV transcription 25 . The association of risk factors with HBV and HCV has been a variable in different studies.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Hepatitis B and Hepatitis C Virus Infections at Premarital Screening Program in Duhok, Iraq

Ramadhan

2018

DMJ

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Background: Viral hepatitis causes increasing mortality worldwide despite all the efforts to control this health problem. Premarital screening program provides an opportunity to detect and manage hepatitis B and hepatitis C viruses. Determination of a carrier status during premarital testing will create awareness between the couples and lead to the protection of the prospective spouse by early vaccination or treatment. The objective of this study is to determine the prevalence of hepatitis B and hepatitis C virus infections among premarital couples in Duhok, Iraq. Subject and Methods: This cross-sectional study was conducted from August 2016 to April 2017 in the clinic and laboratory of the premarital screening program within the preventive health affairs in Duhok-Iraq. The sample size was 2000 persons (1000 males and 1000 females). All persons were tested for HBs Ag, total anti-HBc, and anti-HCV. Results: The age ranged from 14 years to 75 years with a mean of 25.1 years (95% CI = 24.8-25.4 years). The prevalence of HBV infection was 1.1% (N=22), isolated anti-HBc as 3.1% (N=62) and HCV seropositivity was 0.2% (N=4).The factors associated with HBV and HCV were being a health professional (P <0.001), having a history of trauma (P =0.003) and having a family history of HBV or HCV (P<0.001). Conclusions: The prevalence of HBV infection, isolated anti-HBc, and HCV seropositivity is low among the premarital people. Including total anti-HBc in the current premarital screening program will detected anti-HBc which helps in the efforts to control and manage HBV.

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“…In addition, the prevalence of HCV infection is different in different populations. For example, the prevalence of HCV infection in premarital screening population was 0.3%, 14 while that of intravenous drug user population was ranging from 22% to 95% 15 . Therefore, this study set the different prevalence of HCV infection in the population (0.5%, 1% and 10%, respectively), and combined with clinical sensitivity and specificity to calculate PPV and NPV.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of seven rapid diagnostic tests for detection of hepatitis C virus antibodies in China

Chen

Xu³

et al. 2021

Journal of Viral Hepatitis

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Rapid diagnostic tests as an attractive alternative to enzyme immunoassay could identify hepatitis C virus (HCV) infected persons more expeditiously. The availability of high performing and quality‐assured rapid diagnostic tests are essential to scale‐up HCV screening. The study was undertaken to evaluate the performance of seven domestic HCV rapid diagnostic tests kits. The kits were evaluated by using HCV serum panels, including HCV basic panel, analytical specificity panel, mixed titre performance panel, characteristic panel, seroconversion panel, and genotype qualification panel. The results showed that clinical sensitivity, clinical specificity and analytical specificity of seven rapid diagnostic tests kits ranged from 94% (95% CI: 83.2–98.6) to 100% (95% CI: 91.5–100). Furthermore, specimens with HCV genotypes 1b, 2a, 3a, 4a, 5a, 6 could be detected by HCV rapid diagnostic tests kits, whereas specimens with genotypes 1a and 2b could not be detected. Additionally, most HCV rapid diagnostic tests kits had great performance in diagnosing different titres and/or different bands samples, but some low S/CO value specimens may not be fully detected by few rapid diagnostic test kits. In conclusion, seven HCV rapid diagnostic tests reagents presented high sensitivity, specificity, good anti‐interference and detection ability of early infection, which could meet the requirements of clinical HCV antibody screening.

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Hepatitis B and C virus prevalence in couples attending an in vitro fertilization clinic in a tertiary care hospital in Saudi Arabia: comparison with ten years earlier

Cited by 6 publications

References 25 publications

Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study

Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study

Prevalence of Hepatitis B and Hepatitis C Virus Infections at Premarital Screening Program in Duhok, Iraq

Evaluation of seven rapid diagnostic tests for detection of hepatitis C virus antibodies in China

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