Hepatitis-Associated Antigen (Australia Antigen) in Massachusetts Blood Donors

Kliman, Allan; Reid, Nana R.; Lilly, Constance; Morrison, Jean

doi:10.1056/nejm197109302851406

Cited by 39 publications

(9 citation statements)

References 11 publications

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“…In most populations the prevalence of chronic carriers of the hepatitis B virus (HBV) is greater in males than females. This sex difference was reported in 1966 by Blumberg et al in three tropical populations (1) and subsequently confirmed by many investigators in studies of blood donor populations (2)(3)(4)(5)(6)(7)(8), various hospitalized and non-hospitalized populations (9-11), kidney transplant and chronic hemodialysis patients (12), and residents of institutions for the mentally retarded (13,14). Some exceptions to this pattern have been observed (9), including a study in Greece in which the frequency of detection of the surface antigen of HBV (HBsAg) was higher (but not significantly) in fenales (15).…”

supporting

confidence: 67%

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Sex differences in response to hepatitis B infection among patients receiving chronic dialysis treatment.

London¹,

Drew²

1977

Proc. Natl. Acad. Sci. U.S.A.

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supporting

confidence: 67%

“…2). Three patients, two females and one male, became 2562 Medical Sciences: London and Drew (~~~~~~~~~~~~~~5) (4) .C .34 t l t l …”

Section: Methodsmentioning

confidence: 99%

Sex differences in response to hepatitis B infection among patients receiving chronic dialysis treatment.

London¹,

Drew²

1977

Proc. Natl. Acad. Sci. U.S.A.

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“…For example, the blood-donating population contains a significant number of professional donors who are known to have an especially high incidence of HBaAg and anti-HBs [5,10]. In addition, the blood-donating population is variable in origin, with varying economic, social and genetic backgrounds.…”

Section: Discussionmentioning

confidence: 99%

Hepatitis B Antigen and Antibody among Staff Members of an Israeli Hospital and a Kibbutz Population

Sikuler¹,

Dvilansky²,

Skibin³

et al. 1978

Vox Sanguinis

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Until recently, hepatitis type B was thought to be transmitted parenterally. However, much evidence has appeared regarding non-parenteral transmission. Hospital personnel are exposed both ways to this disease. We compared the incidence of hepatitis B surface antigen (HB(s)Ag) and antibody (anti-HB(s)) among 388 workers at a major medical center in Israel with 203 kibbutz residents, using radioimmunoassay procedures. - Of the hospital personnel, 1.8% were found to carry the antigen and 23.9% the antibody. In contrast, 0.5% of kibbutz personnel were antigen-positive and 11.8% carried the antibody. The highest incidence of antibody was found among people born in middle-eastern countries outside of Israel. These results show a significant increase in the exposure of hospital personnel to hepatitis B virus. A marked increase in the frequency of sera positive for anti-HB(s) occurred after the first year of hospital work.

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“…In other studies, particular donor populations have been identified as having a high preva lence of HBsAg, or of posing an increased risk of transmitting hepatitis. Commercial blood donors are perhaps most notable in this respect [1,5,8], but institutionalized [11] and military [8] donor populations have al so been identified as high risk groups.…”

Section: Introductionmentioning

confidence: 99%

Hepatitis-Associated Markers in the American Red Cross Volunteer Blood Donor Population

Dodd¹,

Bastiaans²,

Nath³

et al. 1980

Vox Sanguinis

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The American Red Cross collects blood from a number of defined subsets of the donor population and the proportion of blood collected from each subset varies widely from center to center. A large part of the variation in prevalence of HBsAg may be related to variations in the proportion of blood collected from plants and factories, military units and schools or colleges. We have derived a regression equation, significant at the p˂0.001 level, which links HBsAg prevalence with these collection parameters. Using this equation, we were able to predict the prevalence of HBsAg among first-time donors in 6 of the 9 geographic divisions of the United States with an accuracy exceeding 10%. The predictions for the remaining divisions were within 35% of the actual value. Correlation studies were supported by measurements of true donor prevalence in three blood centers.

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Hepatitis-Associated Antigen (Australia Antigen) in Massachusetts Blood Donors

Cited by 39 publications

References 11 publications

Sex differences in response to hepatitis B infection among patients receiving chronic dialysis treatment.

Sex differences in response to hepatitis B infection among patients receiving chronic dialysis treatment.

Hepatitis B Antigen and Antibody among Staff Members of an Israeli Hospital and a Kibbutz Population

Hepatitis-Associated Markers in the American Red Cross Volunteer Blood Donor Population

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