Hepatitis A outbreaks in China during 2006: application of molecular epidemiology

Cao, Jun; Wang, Yue; Song, Haiyan; Meng, Qingling; Sheng, Li‐Ping; Bian, Tao; W, Mahemuti; Yierhali, Ayiguli; Omata, Masao; Bi, Shengli

doi:10.1007/s12072-008-9116-8

Cited by 33 publications

(32 citation statements)

References 19 publications

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“…In Heilongjiang, which is located in northeastern China, the prevalence of anti-HAV was over 95% in the population > 40 years of age. Yanbian is also located in Northeastern China, and the seroprevalence in our study is consistent with previously published studies on China [21-25]. In this region there are significant differences between the two ethnic groups (i.e., Koreans living in China and indigenous Chinese).…”

Section: Discussionsupporting

confidence: 91%

Seroepidemiology of Hepatitis A Infection in Northeastern China, Korea, and Japan

Yun

Lee

Yoon

et al. 2012

Osong Public Health and Research Perspectives

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ObjectivesThe epidemiological patterns of endemic hepatitis A virus (HAV) are unclear in northeastern Asia depending on the ethnicity of the country in question. The purpose of this study was to investigate the seroprevalence of HAV in northeastern China, South Korea, and Japan.MethodsA total of 1,500 serum samples were collected from five groups of inhabitants (300 each) who were over 40 years of age (Korean Chinese, indigenous Chinese, South Korean, Korean living in Japan, and indigenous Japanese). The samples were screened for antibodies to HAV using an enzyme-linked immunosorbent assay.ResultsPositivity for HAV antibodies was 93.7% (95% confidence interval [CI]: 90.9–96.4) in Koreans living in northeastern China, 99.7% (95% CI: 99.0–100.3) in indigenous Chinese, 98.0% (95% CI: 96.4–99.6) in indigenous Koreans, 33.3% (95% CI: 28.0–38.7) in Koreans living in Japan, and 20.4% (95% CI: 15.8–25.0) in indigenous Japanese persons. The overall anti-HAV prevalence was not significantly different between northeastern China and South Korea, but it was different in Japan.ConclusionsThese results indicate that differences in seroprevalence can be attributed to geological, environmental, and socioeconomic conditions rather than ethnicity.

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Section: Discussionsupporting

confidence: 91%

Seroepidemiology of Hepatitis A Infection in Northeastern China, Korea, and Japan

Yun

Lee

Yoon

et al. 2012

Osong Public Health and Research Perspectives

View full text Add to dashboard Cite

show abstract

“…The anti-HAV IgG prevalence analysis showed an increase from younger groups to older groups. Attributed to the large population, inadequate sanitation, and poor hygiene which favored HAV circulation and transmission, 21 the older population gained high anti-HAV IgG prevalence mainly from natural infection during a long period of time. In contrast, the high prevalence in the group under 5 y old may be principally due to the HAV vaccination.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of 10-year vaccination (2001–2010) for Hepatitis A in Tianjin, China

Zhang

Zhu

Shan

et al. 2014

Human Vaccines & Immunotherapeutics

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“…Çocuklardaki HAV enfeksiyonu genelde asemptomatik iken, erişkinlerdeki enfeksiyon sıklıkla ciddi seyreder (28)(29)(30).…”

Section: Discussionunclassified

Batman Devlet Hastanesine Başvuran Kişilerde Hepatit ve HIV Serolojisinin Sonuçları

...

2012

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Hepatitis A outbreaks in China during 2006: application of molecular epidemiology

Abstract: Contaminated water and suspected ice cream were associated with outbreaks of hepatitis A. Viral genetic analysis may advance field investigations in complex situations.

Cited by 33 publications

References 19 publications

Seroepidemiology of Hepatitis A Infection in Northeastern China, Korea, and Japan

Seroepidemiology of Hepatitis A Infection in Northeastern China, Korea, and Japan

Effectiveness of 10-year vaccination (2001–2010) for Hepatitis A in Tianjin, China

Batman Devlet Hastanesine Başvuran Kişilerde Hepatit ve HIV Serolojisinin Sonuçları

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