Hépatite B chez la population des donneurs de sang au Maroc : comparaison de la prévalence de l’Ag HBs chez les différentes catégories de donneurs

Adouani, B.; Alami, Ramzi S.; Laouina, A.; Bouhlal, N.; Benahadi, A.; Boulahdid, S.; Tazi-Mokha, A.; Mokhtari, A.; Soulaymani, Abdelmajid; Abouyoub, Ahmed; Benajiba, M.

doi:10.1016/j.tracli.2013.03.047

Cited by 2 publications

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“…Previous studies conducted in Morocco on the general population have reported HBV prevalence <2%: 1.66% among the active population [10] and 1.81% in the cross-sectional survey enrolling in the large screening program for hepatitis B and C conducted by the Pasteur Institute of Morocco [11]. Other studies conducted on blood donors in Rabat in 2013 and 2016 have reported the prevalence of 0.8 and 1.34%, respectively [12, 13], suggesting a slight difference in HBsAg prevalence between our recruited patients and the general populations as reported previously.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Hepatitis B Virus Infection Markers among Patients of the Ibn Sina University Hospital Center (Rabat, Morocco)

et al. 2021

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Introduction: Viral hepatitis B is a global scourge affecting millions of people worldwide. In Morocco, hepatitis B is considered a public health problem, and available data converge to consider Morocco as a country with intermediate endemicity. In the present study, we have planned to evaluate the HBV prevalence in Morocco on a large scale and to assess the prevalence of different serological markers for better management of this infection in Morocco. Methods: This study was conducted on 18,877 patients referring to the Ibn Sina University Hospital Center of Rabat, Morocco. HBV serological markers including HBsAg, HBsAb, HBeAg, HBeAb, and total HBcAb were assessed by immune-enzymatic assays. The quantification of HBV DNA was performed by real-time PCR. Results: The overall prevalence of positive cases for HBsAg, HBsAb, and total HBcAb was 2.47%, 27.66%, and 21.2%, respectively. From 141 patients with an isolated HBcAb serological profile (HBcAb+/HBsAb−/HBsAg−), HBV DNA was detected in 10 patients, representing a rate of 7.09%. In the present study, up to 95.78% of HBV chronic carriers were negative for HBeAg. Conclusion: This study highlights a higher prevalence of HBsAg in the hospital-based population than the general population reported previously in Morocco and a very low HBV immunization coverage. Of particular interest, detectable HBV DNA levels in isolated HBcAb patients show that exclusive HBsAg screening cannot eliminate the risk of HBV transmission in certain cases. Many efforts are then mandatory to promote serological testing and increase the vaccination rate to limit viral dissemination for better management of this disease in Morocco.

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Section: Discussionmentioning

confidence: 99%

Prevalence of Hepatitis B Virus Infection Markers among Patients of the Ibn Sina University Hospital Center (Rabat, Morocco)

et al. 2021

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“…When the hepatitis C screening test is introduced, the search for increased ALT levels is not identifiable in terms of improving transfusion safety according to the WHO and for this reason, routine ALT testing of blood donors is not recommended [8]. In Morocco, the systematic determination of ALT in blood donors is obligatory [23]. In France, the introduction of viral genomic screening of blood donors has cancelled the contribution of the ALT test to blood safety in relation to the known hepatotropic virus.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of hepatitis B and C in blood transfusion center, Oujda Morocco (2013-2015)

Boubker¹,

Zerrouki²,

Sidqi³

et al. 2019

Pan Afr Med J

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Viral hepatitis is a serious public health problem. Its epidemiology is not precisely known in Morocco. Our objective was to assess the prevalence of HBV and HCV in a particular population of “blood donors” at the Regional Blood Transfusion Centre in Oujda. A retrospective study was conducted from May 1, 2013 to May 31, 2015. Thirty-one thousand nine hundred and fifty-two blood donors were tested. Antigen detection was made according to ELISA technique (MonolisaTMHBs Ag ULTRA). HCV research was performed by ELISA using the kit « Monolisa HCV Ag-Ab ULTRA ». 177 blood donors included, they are divided into 155 male (87.6%) and 22 female (12.4%) subjects with a ratio of 7. The average age was 37.64 ± 12 years. Six cases were positive for HCV with an overall prevalence of 0.02%. The population study by sex shows a prevalence of 0.004% for 23177 male sera and 0.057% for 8775 female sera. Six donors were HCV positive, of which 05 were female (83.33%) and one was male (16.66%). The average age was 43 ± 14 years. Co-infection with HCV HBV-HCV and HCV-Syphilis and HCV-HIV are absent. Co-infection with HBV and HIV was found in one case. HBV-syphilis co-infection was found in 04 cases. Chronic viral hepatitis is a real global health problem. Its prevalence is currently estimated at 0.55% for HBV and 0.02% for HCV, reclassifying Morocco as a low endemic area. The prevention remains the most effective method to successfully control HBV and HCV infection.

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Hépatite B chez la population des donneurs de sang au Maroc : comparaison de la prévalence de l’Ag HBs chez les différentes catégories de donneurs

Cited by 2 publications

References 0 publications

Prevalence of Hepatitis B Virus Infection Markers among Patients of the Ibn Sina University Hospital Center (Rabat, Morocco)

Prevalence of Hepatitis B Virus Infection Markers among Patients of the Ibn Sina University Hospital Center (Rabat, Morocco)

Prevalence of hepatitis B and C in blood transfusion center, Oujda Morocco (2013-2015)

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