Hepatic Venous Occlusion Causes More Impairment After Reperfusion Compared with Portal Clamping in a Murine Model

Yan, Sheng; Zhou, Bo; Zhang, Qiyi; Li, Zhiwei; Shao, Yi; Chen, Hui; Zheng, Shusen

doi:10.1016/j.jss.2009.12.006

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-Partial Hepatic Ischemia Reperfusion Murine Model1

Animal Models For Studying Cell‐assisted Drug Delivery1

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Cited by 4 publications

(2 citation statements)

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“…The hepatic left lobe blood flow was transiently blocked using a straight micro clip (Roboz Surgical Instrument). After 75 min of ischemia, the clamp was removed to allow reperfusion (20). Mice were sacrificed after 3, 6, 24, 48 or 72 hours of reperfusion.…”

Section: -Partial Hepatic Ischemia Reperfusion Murine Modelmentioning

confidence: 99%

Inositol 1,4,5-trisphosphate receptor type 3 plays a protective role in hepatocytes during hepatic ischemia-reperfusion injury

et al. 2020

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Section: -Partial Hepatic Ischemia Reperfusion Murine Modelmentioning

confidence: 99%

Inositol 1,4,5-trisphosphate receptor type 3 plays a protective role in hepatocytes during hepatic ischemia-reperfusion injury

et al. 2020

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“…The complexity of the liver vascular system allows the study of the occlusion of hepatic arteries and veins in separate or combined setups . A number of hepatocyte‐specific drug delivery systems, such as liposomes, recombinant high‐density lipoproteins, and polymers, have recently been developed for the selective delivery of therapeutic drugs (Figure ) …”

Section: Animal Models For Studying Cell‐assisted Drug Deliverymentioning

confidence: 99%

Cell‐Based Drug Delivery and Use of Nano‐and Microcarriers for Cell Functionalization

Timin

Litvak

Gorin

et al. 2017

Adv Healthcare Materials

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Cell functionalization with recently developed various nano- and microcarriers for therapeutics has significantly expanded the application of cell therapy and targeted drug delivery for the effective treatment of a number of diseases. The aim of this progress report is to review the most recent advances in cell-based drug vehicles designed as biological transporter platforms for the targeted delivery of different drugs. For the design of cell-based drug vehicles, different pathways of cell functionalization, such as covalent and noncovalent surface modifications, internalization of carriers are considered in greater detail together with approaches for cell visualization in vivo. In addition, several animal models for the study of cell-assisted drug delivery are discussed. Finally, possible future developments and applications of cell-assisted drug vehicles toward targeted transport of drugs to a designated location with no or minimal immune response and toxicity are addressed in light of new pathways in the field of nanomedicine.

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Ischemic preconditioning improves liver tolerance to congestion–reperfusion injury in mice

Zhang

Yan

Tian

et al. 2014

Journal of Surgical Research

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Hepatic Venous Occlusion Causes More Impairment After Reperfusion Compared with Portal Clamping in a Murine Model

Cited by 4 publications

References 20 publications

Inositol 1,4,5-trisphosphate receptor type 3 plays a protective role in hepatocytes during hepatic ischemia-reperfusion injury

Inositol 1,4,5-trisphosphate receptor type 3 plays a protective role in hepatocytes during hepatic ischemia-reperfusion injury

Cell‐Based Drug Delivery and Use of Nano‐and Microcarriers for Cell Functionalization

Ischemic preconditioning improves liver tolerance to congestion–reperfusion injury in mice

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