Hepatic Metastases: Detection with Multi–Detector Row CT, SPIO-enhanced MR Imaging, and Both Techniques Combined

Onishi, Hiromitsu; Murakami, Takamichi; Kim, Tonsok; Hori, Masatoshi; Iannaccone, Riccardo; Kuwabara, Masachika; Abe, Hisashi; Nakata, S; Osuga, Keigo; Tomoda, Kaname; Passariello, Roberto; Nakamura, Hajime

doi:10.1148/radiol.2383041825

Cited by 67 publications

(37 citation statements)

References 23 publications

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“…SPIOand Gd-EOB-DTPA-enhanced MR images are used to improve detection and characterization of focal hepatic lesions in clinical studies. 9,10 On SPIO-enhanced MR imaging, we visualized the present BDA as an area of diminished SPIO uptake, such as that observed in hepatic metastatic lesions. During the hepatobiliary phase of Gd-EOB-DTPA-enhanced MR imaging, our case and one previously reported case 5 demonstrated distinct hypointensity.…”

Section: Magnetic Resonance In Medical Sciencesmentioning

confidence: 90%

Intrahepatic Bile Duct Adenoma Mimicking Hepatic Metastasis: Case Report and Review of the Literature

et al. 2013

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We present a case of bile duct adenoma that mimicked hepatic metastasis from gastric cancer. The adenoma exhibited prolonged enhancement on dynamic computed tomography, hyperintensity on diŠusion-weighted imaging, and diminished uptake of superparamagnetic iron oxide and gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid on magnetic resonance imaging, resembling those of adenocarcinomas. Knowledge of the imagingˆndings of this rare entity may aid correct diagnosis.

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Section: Magnetic Resonance In Medical Sciencesmentioning

confidence: 90%

Intrahepatic Bile Duct Adenoma Mimicking Hepatic Metastasis: Case Report and Review of the Literature

et al. 2013

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“…However, magnetic resonance imaging (MRI) has improved markedly, especially in combination with new contrast agents [10,11,14]. Constant developments in liver imaging have resulted in many trials assessing the optimal imaging strategy, but contradictory results have been reported [11,12,13,14,15,16,17]. Currently, there is no uniform recommendation for the use of either MSCT or MRI for evaluation of CRLM in patients who did not receive NAC.…”

Section: Introductionmentioning

confidence: 99%

Accuracy of Multislice Liver CT and MRI for Preoperative Assessment of Colorectal Liver Metastases after Neoadjuvant Chemotherapy

Kessel¹,

Leeuwen

Bosch

et al. 2011

Dig Surg

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Introduction: To determine the best imaging modality for preoperative detection, characterization and measurement of colorectal liver metastases (CRLM) after neoadjuvant chemotherapy (NAC). Methods: A total of 79 lesions in 15 patients with CRLM were included. Following NAC, all patients received multislice liver CT (MSCT) and magnetic resonance imaging (MRI) that were scored by two observers for lesion number, type, diameter (mm) and segmental location. Intraoperative findings, histopathology and follow-up imaging were used as reference standard for surgically treated patients; non-surgical candidates underwent follow-up imaging. Results: Lesion detection rate was similar for MSCT and MRI (76 and 80%, respectively, p = 0.648). Lesion characterization was significantly superior (p = 0.021) at MRI (89%, ĸ 0.747, p = 0.001) compared to MSCT (77%, ĸ 0.235, p = 0.005). Interobserver variability for diameter measurement was not significant at MRI (p = 0.909 [95% CI –1.245 to 1.395]), but significant at MSCT (p = 0.028 [95% CI –3.349 to –2.007]). Differences in diameter measurement were independent of observer (p = 0.131), and no statistical effect from imaging modality on diameter measurement was observed (p = 0.095). Conclusion: MRI is superior to MSCT in preoperative characterization and measurement of CRLM after NAC. Lesion detection rates for both modalities are comparable.

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“…CT should be performed with native images as well as after using modern nonionic, iodine-containing water-soluble contrast agents; multidetector helical CT is today's standard [24][25][26][27] . For helical CT, 5 mm reconstructions should be used allowing a minimum-sized lesion of 10 mm to be detected.…”

Section: Reviewmentioning

confidence: 99%

“…Multisplice spiral CT has a sensitivity for the detection of liver metastasis of 65-85% [24][25][26][27] , thus making it the method of choice for staging urogenital cancer. Contrastenhanced MRI increases the sensitivity for detecting metastases to 90% as compared to only 70% of unenhanced MRI [26,27] .…”

Section: Reviewmentioning

confidence: 99%

Imaging Studies in Metastatic Urogenital Cancer Patients Undergoing Systemic Therapy: Recommendations of a Multidisciplinary Consensus Meeting of the Association of Urological Oncology of the German Cancer Society

et al. 2010

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Introduction: Imaging studies are an integral and important diagnostic modality to stage, to monitor and follow-up patients with metastatic urogenital cancer. The currently available guidelines on diagnosis and treatment of urogenital cancer do not provide the clinician with evidence-based recommendations for daily practice. Objectives: To develop scientifically valid recommendations with regard to the most appropriate imaging technique and the most useful time interval in metastatic urogenital cancer patients undergoing systemic therapy. Methods: A systematic literature review was performed searching MedLine, Embase and Web of Science databases using the terms prostate, renal cell, bladder and testis cancer in combination with the variables lymph node, lung, liver, bone metastases, chemotherapy and molecular therapy, and the search terms computed tomography, magnetic resonance imaging and positron emission tomography were applied. A total of 11,834 records were retrieved from all databases. The panel reviewed the records to identify articles with the highest level of evidence using the recommendation of the US Agency for Health Care Policy and Research. Conclusions: Contrast-enhanced computed tomography remains the standard imaging technique for monitoring of pulmonary, hepatic and lymph node metastases. Bone scintigraphy is still the most widely used imaging technique for the detection and follow-up of osseous lesions. For clinical trials it might be replaced by either PET-CT or MRI of the skeletal axis. Response assessment for patients treated with cytotoxic regime is best performed by the RECIST/WHO criteria; treatment response to molecular triggered therapy is best assessed by CT evaluating decrease in tumor size and density. Cross-sectional imaging studies for response assessment might be obtained after each 2 cycles of systemic therapy to early stratify responders from non-responders.

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Hepatic Metastases: Detection with Multi–Detector Row CT, SPIO-enhanced MR Imaging, and Both Techniques Combined

Cited by 67 publications

References 23 publications

Intrahepatic Bile Duct Adenoma Mimicking Hepatic Metastasis: Case Report and Review of the Literature

Intrahepatic Bile Duct Adenoma Mimicking Hepatic Metastasis: Case Report and Review of the Literature

Accuracy of Multislice Liver CT and MRI for Preoperative Assessment of Colorectal Liver Metastases after Neoadjuvant Chemotherapy

Imaging Studies in Metastatic Urogenital Cancer Patients Undergoing Systemic Therapy: Recommendations of a Multidisciplinary Consensus Meeting of the Association of Urological Oncology of the German Cancer Society

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