Hepatic Metastasectomy for Soft‐Tissue Sarcomas: Is It Justified?

Abstract

Patients who have hepatic metastases that are functionally and technically resectable should be considered for surgery because this treatment offers the chance for long-term survival (>5 years).

Liver resection for metastatic soft tissue sarcoma: An analysis of prognostic factors

“…This recurrence rate is significantly lower compared with the published data, which ranges from 59.3% to 94% [16,20,22,24]. In all of these studies the liver was found to be the most common site of recurrent disease, ranging from 43.7% to 88%.…”

“…However, on multivariate analysis, DFI of more than two years was the only predictor of outcome. This was reconfirmed in the recent publication of Rehders et al [22]. Pawlik et al concluded that patients who were treated with adjuvant chemotherapy had a longer median overall survival compared with those who underwent surgery alone [16].…”

“…The present study demonstrated that the overall survival was improved if the histology of the primary tumour was non-leiomyosarcoma, the tumour was of low/ intermediate grade and the microscopic resection margin was clear of tumour. None of the other studies have identified these factors as predictors of survival [16,[20][21][22][23][24].…”

Management of liver metastases from gastrointestinal stromal tumors: where do we stand?

“…Four studies were excluded from our analysis (10)(11)(12)(13). Three of them reported results on additional malignancies and did not fulfill our inclusion criteria (10,11,13).…”

“…Three of them reported results on additional malignancies and did not fulfill our inclusion criteria (10,11,13). The forth study in addition to including LM from various sarcomas also encompassed radiofrequency ablation as a therapeutic strategy (12).…”