Hepatic hemangiomas

Hobbs, K. E. F.

doi:10.1007/bf01658669

Cited by 46 publications

(30 citation statements)

References 21 publications

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“…Incidence rate 2% in USA & the prevalence rate at necropsy is 7.4%, usually see in multipara women, more female predominance and occur most frequently at age 30-50 years [1,2]. Our patient is 31years old and she has no children.…”

Section: Discussionmentioning

confidence: 91%

“…Hemangioma is the most common benign tumour affecting the liver [1,2]. Hepatic haemangioma are mesenchymal in origin and usually are solitary.…”

Section: Discussionmentioning

confidence: 99%

“…Steroid therapy [6], oestrogen therapy, and pregnancy [7,8] can increase the size of an already existing hemangioma. Our patient was on inhalational steroid therapy for her asthmatic condition and was also on oral contraceptive pills for her polycystic ovarian disease.Incidence rate 2% in USA & the prevalence rate at necropsy is 7.4%, usually see in multipara women, more female predominance and occur most frequently at age 30-50 years [1,2]. Our patient is 31years old and she has no children.…”

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confidence: 91%

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Spontaneous Rupture of Liver Haemangioma-A Case Report & Review of Literature

Islam¹,

Naraynsingh²

2014

Surgery

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A 31yrs old female patient presented with three day history of sudden right upper quadrant pain which progressively worsened over the last 24 hours. She is a known asthmatic controlled by Nasacort inhaler and also a known case of polycystic ovary diseases using oral contraceptive pills over the last 9 years.On physical examination revealed a young female in mild painful distress. Her mucous membrane was pink and moist. She was warm to touch with a temperature of 38.4°C and her vitals were within normal limit. Abdominal examination revealed moderate tenderness in right upper quadrant with mild guarding but no rebound tenderness.An USS of abdomen revealed a normal gall bladder with no peri-cholecystic fluids or gall stones with a normal CBD. However, a 7.77 x 9.42 cm cystic mass was noted in right lobe of liver and there was no free fluid ( Figure 1). A CXR revealed right basal consolidation. Her WBC was elevated 26.2 and she was also anaemic with an Hb of 11 mg/dl. Her renal function as well as electrolytes were within normal limit, however her liver enzymes were elevated AST-600, ALT-1900, ALP-238, GGT-166 with normal serum bilirubin and amylase level.After 24 hours her pain became severe and she became tachycardic with a pulse of 130 bpm with persistently elevated temperature (38.0°C). Her blood pressure and Spo2 was normal. There was decreased air entry at right lung base. Abdominal examination revealed marked tenderness with guarding but no rebound tenderness and there was sluggish bowel sound. Patient Hb had dropped from 10 gm/dl to 8 gm/dl. An Urgent CT scan of abdomen and pelvis with intravenous contrast revealed that the cyst (haemangioma) has ruptured with free fluid (blood) in Morrison pouch and in right Para-colic gutter (Figure 2). Subsequently patient developed moderate respiratory distress and was reviewed by medicine specialist. A Spiral CT of the chest-revealed mild right pleural effusion with fluid in oblique fissure but no evidence of pulmonary embolism. An MRI of abdomen was also performed which reconfirm the ruptured hepatic haemangioma. Patient was admitted in HDU and was managed successfully and discharged home on day-12.Patient had a high ESR of 39 and her liver function test became normal. Her serum alpha fetoprotein, CEA, Ca 19-9, anti-nuclear DNA levels were within normal limit. DiscussionHemangioma is the most common benign tumour affecting the liver [1,2]. Hepatic haemangioma are mesenchymal in origin and usually are solitary. Haemangioma are composed of masses of blood vessels that are atypical or irregular in arrangement and size. Exact aetiology remains unknown [3][4][5].Several pharmacologic agents have been postulated to promote tumour growth. Steroid therapy [6], oestrogen therapy, and pregnancy [7,8] can increase the size of an already existing hemangioma. Our patient was on inhalational steroid therapy for her asthmatic condition and was also on oral contraceptive pills for her polycystic ovarian disease.Incidence rate 2% in USA & the prevalence rate at necropsy is 7.4%, usual...

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Section: Discussionmentioning

confidence: 91%

“…Hemangioma is the most common benign tumour affecting the liver [1,2]. Hepatic haemangioma are mesenchymal in origin and usually are solitary.…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 91%

See 1 more Smart Citation

Spontaneous Rupture of Liver Haemangioma-A Case Report & Review of Literature

Islam¹,

Naraynsingh²

2014

Surgery

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“…There is no evidence that these lesions are precancerous. It occurs most commonly in men, especially in the fifth and sixth decades of life [29,30]. Usually asymptomatic, they are incidental findings at autopsy or surgery.…”

Section: Macroregenerative Nodule (Multiacinar Regenerative Nodule)mentioning

confidence: 99%

Benign neoplasms of the liver

Porayko

Choudhary

2001

Curr Treat Options Gastro

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Tumors of the liver often are discovered incidentally in asymptomatic individuals during diagnostic imaging or exploratory laparotomy performed for alternative reasons. Hemangiomas are the most common benign liver tumors, followed in prevalence by focal nodular hyperplasia (FNH); other benign tumors are rare. The growth and development of hemangiomas, FNH, and hepatic adenomas especially, have been linked to hormonal (eg, estrogen) stimulation. Differentiating between benign and malignant neoplasms of the liver can be challenging. Radiologic imaging is essential for preliminary identification and classification of hepatic tumors, but tissue biopsy or surgical excision sometimes is required for a definitive diagnosis. Individuals with hemangioma or FNH usually are asymptomatic, have a benign course, and can be managed conservatively. In contrast, hepatic adenomas need to be followed more carefully and often are excised to provide symptomatic relief, remove the risk of rupture, and avoid potential malignant transformation. Liver transplantation in patients with benign hepatic neoplasms is exceedingly uncommon, and is recommended only when alternative methods of treatment are not feasible or have failed to control significant symptoms.

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“…Liver tumors in adult patients have been investigated from various points of view, but reports of liver tumors in children and young adults are relatively rare and deal mainly with histologic findings or surgical procedures [1][2][3][4][5]. Although diverse hepatic diseases have been explored by sonography (US) and more recently by color Doppler US, US or color Doppler findings of liver tumors in children and young patients are rarely reported [6 -9].…”

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confidence: 99%