Abstract:Objective The diagnosis of biliary atresia (BA) can be challenging as its histopathologic features overlap with those of other pediatric cholestatic liver diseases. We aimed to study the diagnostic value of hepatic interferon-c (IFN-c) and CD68 immunostaining in the differentiation of BA from other causes of neonatal cholestasis (NC).Patients and methods Hepatic IFN-c and CD68 immunostaining were investigated in 69 patients divided on the basis of the diagnosis into the BA group (n = 34) and the non-BA group (… Show more
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