Hepatic Dysfunction in Patients of Dengue Viral Infection in Kota Region

Seervi, Naveen; Meena, Shivraj; Saluja, Manoj; Meena, Shyam Charan; Shringi, Prashant; Saini, Pankaj

doi:10.1016/j.jceh.2015.07.147

Cited by 1 publication

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“…Ascites, pleural and pericardial effusion, and GBWT were the most common ultrasound findings in dengue. 18,19,30,35,41,53, By contrast, only one study in this review found pulmonary B-lines suggestive of pulmonary edema. 18 Given the 97% sensitivity of ultrasound for the diagnosis of pulmonary edema, this finding may suggest a relative dearth of vascular leakage into the pulmonary airspace and parenchyma in dengue as compared with the peritoneal cavity, thoracic cavity, pericardial sac, and gallbladder wall, or limited exploration of this sign.…”

Section: Discussionmentioning

confidence: 63%

“…However, many studies considered competing clinical diagnoses such as malaria, typhoid, viral hepatitis, and other febrile illnesses. 23,[39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57] More importantly, a majority of studies (82%) confirmed suspected cases with laboratory testing, assuring reviewers that included patients were likely infected with dengue. This point further highlights ultrasound's potential to differentiate severe dengue from other febrile illnesses in which vascular leakage is not seen, although further research in this area is required.…”

Section: Discussionmentioning

confidence: 99%

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Ultrasound in Dengue: A Scoping Review

Dewan

Zuluaga

Osório

et al. 2021

The American Journal of Tropical Medicine and Hygiene

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To improve dengue triage and treatment decisions, the WHO recommends classifying the disease as dengue with or without warning signs or severe dengue. Vascular leakage is a key component of the pathophysiology of severe dengue and is detectable by ultrasound. The objective of this scoping review is to describe the primary literature on the use of ultrasound in dengue, summarize the findings, and identify knowledge gaps. Our database search retrieved 1,489 records which were reduced to 177 studies following eligibility screening. Descriptive analyses were conducted. Results showed most studies are from South Asia (n = 92, 52%) and assessed hospitalized dengue patients (130, 82%). Radiologists were the most reported ultrasonographers (14, 8%), and conventional ultrasound (39, 68%) was preferred over portable (9, 16%). The most common ultrasound findings in dengue were ascites (107, 60%), pleural effusion (102, 58%), and gallbladder wall thickening (97, 55%). However, the lack of a standard protocol to perform the ultrasound examination in dengue patients hinders conclusions about the frequency of ultrasound findings in dengue. Given the progress of current ultrasound technology, a focused point-of-care ultrasound protocol for early detection of vascular leakage in dengue is needed to generate the evidence required for its implementation in routine care.

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