Hepatic and metabolic changes in surgical colic patients: a pilot study

Underwood, Charlie J.; Southwood, Louise L.; Walton, Raquel M.; Johnson, Amy

doi:10.1111/j.1476-4431.2010.00597.x

Cited by 36 publications

(33 citation statements)

References 23 publications

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“…Early provision of energy is not the goal of an early refeeding programme, although refeeding can prevent hypertriglyceridaemia and eliminate the need for parenteral nutrition (Underwood et al . ). However, early refeeding can only be tolerated if the anastomosis is fully functional.…”

Section: Post‐operative Feedingmentioning

confidence: 97%

Post‐operative reflux – a surgeon's perspective

Freeman

2017

Equine Veterinary Education

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Summary Post‐operative ileus (POI) is a well‐recognised complication of colic surgery that accounts for a high proportion of post‐operative deaths. Although much has been written about the pathophysiology and management of POI in horses, most studies seem to apply research findings to the clinical case without full regard for the clinical evidence. Although much attention has focused recently on the role of inflammation, this narrow focus might explain our failure to make important advances in managing horses with this complication. This commentary is offered to redirect our current thinking about POI away from an approach that predominantly emphasises a functional disorder and medical management, to one that addresses surgical prevention.

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Section: Post‐operative Feedingmentioning

confidence: 97%

Post‐operative reflux – a surgeon's perspective

Freeman

2017

Equine Veterinary Education

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“…In fact, the cardiovascular criteria used in the SOFA score performed more robustly than the MODS score . Whenever available, data in the literature collected from other institutions were incorporated herein for determining the cutoffs for each score within an organ system . Furthermore, the use of ROC analysis on the data set to define cut points for organ scores was deliberately avoided to prevent choosing criteria that were only associated with nonsurvival as the goal of the score was to reflect a range of organ dysfunction.…”

Section: Discussionmentioning

confidence: 99%

“…Individual organ dysfunction has been reported in horses with acute gastrointestinal (GI) disease . Criteria for MODS in horses were proposed recently based on MODS criteria used in people, referred to herein as MODS EQ, but remain unvalidated .…”

mentioning

confidence: 99%

Scoring System for Multiple Organ Dysfunction in Adult Horses with Acute Surgical Gastrointestinal Disease

McConachie

Giguère

Barton

2016

Veterinary Internal Medicne

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BackgroundThe prevalence of multiple organ dysfunction syndrome (MODS) in horses with acute surgical gastrointestinal (GI) disease is unknown. Currently, there are no validated criteria to confirm MODS in adult horses.ObjectivesTo develop criteria for a MODS score for horses with acute surgical colic (MODS SGI) and evaluate the association with 6‐month survival. To compare the MODS SGI score with a MODS score extrapolated from criteria used in people (MODS EQ).AnimalsAdult horses that required exploratory laparotomy (n = 62) for colic. Healthy adult horses undergoing elective surgical procedures (n = 12) established the reference range of some variables.MethodsProspectively, a MODS SGI score was developed based on organ‐specific criteria established from a literature review, data collection, and clinical judgment. Data for scoring each horse were collected on Days 1 and 2 postoperatively. Horses were scored retrospectively using both scoring criteria. The prognostic performance of the MODS SGI score and its overall performance compared with the MODS EQ score were assessed with receiver operating characteristic (ROC) curve analysis.ResultsThe MODS SGI score had excellent performance for predicting 6‐month survival with an area under the ROC curve (AUC) of 0.95 (95% CI: 0.87–0.99). The AUC for the MODS SGI score was significantly higher than the MODS EQ (AUC: 0.76; 0.63–0.86).Conclusions and Clinical ImportanceThe MODS SGI score predicts 6‐month survival from discharge in horses with acute surgical colic. The MODS SGI score performed better than a score extrapolated from human scoring systems.

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“…Clinical pathology changes associated with the hepatobiliary system are also observed very commonly in horses with colic (Underwood et al . ). A combination of hyperglycaemia (e.g.…”

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confidence: 97%

The duodenum: An uncommon site of surgical lesions

Southwood

2014

Equine Veterinary Education

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Summary It is fortunate for the horse that duodenal lesions requiring surgical correction occur infrequently. Despite being an uncommon site of obstruction, palpation of the duodenum should be part of a complete surgical abdominal exploration. Horses with proximal obstruction typically have large volumes of reflux following passage of a nasogastric tube. Biochemistry abnormalities may include hypochloraemia and hyperglycaemia particularly with a complete or strangulating obstruction. Early surgical treatment of a duodenal volvulus may result in a favourable outcome.

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Hepatic and metabolic changes in surgical colic patients: a pilot study

Abstract: Alterations in metabolism and hepatobiliary function are common in colic patients. The results of this study provide further prognostic indices for colic patients and highlight areas for improvement in patient management.

Cited by 36 publications

References 23 publications

Post‐operative reflux – a surgeon's perspective

Post‐operative reflux – a surgeon's perspective

Scoring System for Multiple Organ Dysfunction in Adult Horses with Acute Surgical Gastrointestinal Disease

The duodenum: An uncommon site of surgical lesions

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