Hepatic Amebiasis Among Patients in a Public Teaching Hospital

Clinical Manifestations and Risk Factors of Amebic Liver Abscess in Southeast Taiwan Compared with Other Regions of Taiwan

“…1,7 It remains unclear why there is a sex difference, although several hypotheses have been proposed, including heavy alcohol consumption by men, 8 hormonal effects in pre-menopausal women that may modulate infection, 9 and a possible protective effect of iron deficiency anemia among menstruating women. 10 Our study revealed two risk factors for ALA, alcoholism and diabetes, that differed from other regions of Taiwan, although they are common risk factors for ALA. 1,5,7 Taitung, located in southeastern Taiwan, has the highest proportion of aboriginal residents, 11 and a high prevalence of alcoholism among aborigines was reported (44.2-55.2%) during the 1990s.…”

“…The radiographic characteristics of ALA were also similar in all regions, 2,4-6 such as the finding of a large single lesion in the right liver lobe of liver, and they were common findings in other reports. 1,[7][8][9][10]16,17 Thus, the clinical characteristics and radiographic characteristics of ALA are similar throughout the world, and they are not different in different groups based on geographic region, HIV infection, or severity of disease. However, elevated bilirubin levels (2.97 mg/dL) and low albumin levels (2.45 g/dL) were noted in our study, and these risk factors indicate a poor prognosis.…”

Entamoeba histolytica

“…Complications of amebic liver abscess include its rupture and secondary bacterial infection (Petri and Singh, 1999). The collection of pus in the liver as an abscess may present acutely, with fever and right upper abdominal tenderness, and subacutely, also with abdominal pain and prominent weight loss (Shandera et al, 1998). Moreover, the skin and the white of the eyes become yellow or jaundiced.…”

Mechanisms of Hepatocellular Dysfunction and Regeneration: Enzyme Inhibition by Nitroimidazole and Human Liver Regeneration

“…Amoebic liver-abscesses arise from haematogenous spread (probably via the portal circulation) of amoebic trophozoites that have breached the colonic mucosa. [Thompson et al 1985, Abuabara et al 1982, Shandera et al 1998, Barnes et al 1987, Adams 1977, Lancet 2003. Effective nitroimidazole treatment and rapid diagnosis showed the mortality rates to 1-3%.…”

“…In previous reports, patient symptoms, leucocytosis without eosinophilia, mild anaemia, raised concentrations of alkaline phosphatase, and a high rate of erythrocyte sedimentation were the most common laboratory findings. [ Thompson et al 1985, Abuabara et al 1982, Shandera et al 1998, Barnes et al 1987, Adams 1977, Lancet 2003]. …”